Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center
Objective: Cytomegalovirus (CMV) is the most common viral infection. In this study, we discussed the results of pregnant women who underwent antenatal CMV screening in a tertiary center and the value of CMV antenatal screening. Methods: For this retrospective study, the data of pregnant patients wit...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2023-09-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-84042 |
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| author | Duygu TUGRUL ERSAK Izzet OZGURLUK Ayse Gulcin BASTEMUR Esra GULEN YILDIZ Selcan SINACI Ezgi TURGUT Ozgur KARA Atakan TANACAN Dilek SAHIN |
| author_facet | Duygu TUGRUL ERSAK Izzet OZGURLUK Ayse Gulcin BASTEMUR Esra GULEN YILDIZ Selcan SINACI Ezgi TURGUT Ozgur KARA Atakan TANACAN Dilek SAHIN |
| author_sort | Duygu TUGRUL ERSAK |
| collection | DOAJ |
| description | Objective: Cytomegalovirus (CMV) is the most common viral infection. In this study, we discussed the results of pregnant women who underwent antenatal CMV screening in a tertiary center and the value of CMV antenatal screening.
Methods: For this retrospective study, the data of pregnant patients with antenatal CMV screening test results between 2019 and 2022 were obtained from hospital records. CMV immunoglobulin M (IgM), CMV IgG, anti-IgG avidity test results, amniocentesis, CMV polymerase chain reaction (PCR), and the outcome of the babies were recorded.
Results: A total of 31,912 CMV IgM and 26,969 CMV IgG tests were performed. CMV IgG seropositivity was observed in 78.99% of pregnant women, and 0.09% of the pregnant women were confirmed to have a positive CMV IgM test result. Pregnant women with positive IgM accompanying low avidity were referred to perinatology clinics for detailed ultrasonography and amniocentesis. Only 3 of the 44 pregnant women who underwent amniocentesis were confirmed to have positive CMV PCR testing.
Conclusions: CMV screening should be preserved for pregnant women with ultrasonographic findings at high risk of congenital CMV infection. |
| format | Article |
| id | doaj-art-3a9fda939f9245d688c771053393b2b7 |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-3a9fda939f9245d688c771053393b2b72025-01-30T07:02:58ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062023-09-0138316717110.4274/MMJ.galenos.2023.84042MEDJ-84042Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary CenterDuygu TUGRUL ERSAK0Izzet OZGURLUK1Ayse Gulcin BASTEMUR2Esra GULEN YILDIZ3Selcan SINACI4Ezgi TURGUT5Ozgur KARA6Atakan TANACAN7Dilek SAHIN8University of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyUniversity of Health Sciences Turkey, Ankara City Hospital, Clinic of Obstetrics and Gynecology, Ankara, TurkeyObjective: Cytomegalovirus (CMV) is the most common viral infection. In this study, we discussed the results of pregnant women who underwent antenatal CMV screening in a tertiary center and the value of CMV antenatal screening. Methods: For this retrospective study, the data of pregnant patients with antenatal CMV screening test results between 2019 and 2022 were obtained from hospital records. CMV immunoglobulin M (IgM), CMV IgG, anti-IgG avidity test results, amniocentesis, CMV polymerase chain reaction (PCR), and the outcome of the babies were recorded. Results: A total of 31,912 CMV IgM and 26,969 CMV IgG tests were performed. CMV IgG seropositivity was observed in 78.99% of pregnant women, and 0.09% of the pregnant women were confirmed to have a positive CMV IgM test result. Pregnant women with positive IgM accompanying low avidity were referred to perinatology clinics for detailed ultrasonography and amniocentesis. Only 3 of the 44 pregnant women who underwent amniocentesis were confirmed to have positive CMV PCR testing. Conclusions: CMV screening should be preserved for pregnant women with ultrasonographic findings at high risk of congenital CMV infection.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-84042cytomegalovirusantenatal screeningpregnancyprevalencefetal infection |
| spellingShingle | Duygu TUGRUL ERSAK Izzet OZGURLUK Ayse Gulcin BASTEMUR Esra GULEN YILDIZ Selcan SINACI Ezgi TURGUT Ozgur KARA Atakan TANACAN Dilek SAHIN Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center Medeniyet Medical Journal cytomegalovirus antenatal screening pregnancy prevalence fetal infection |
| title | Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center |
| title_full | Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center |
| title_fullStr | Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center |
| title_full_unstemmed | Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center |
| title_short | Results of Routine Antenatal Screening for Cytomegalovirus at a Tertiary Center |
| title_sort | results of routine antenatal screening for cytomegalovirus at a tertiary center |
| topic | cytomegalovirus antenatal screening pregnancy prevalence fetal infection |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-84042 |
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