Novel ribosome biogenesis-related biomarkers and therapeutic targets identified in psoriasis

Novel ribosome biogenesis-related biomarkers and therapeutic targets identified in psoriasis

Abstract Psoriasis is an immune-mediated chronic inflammatory disease. Increasing evidence suggests a close association between ribosome biogenesis (RiboSis) and the pathogenesis of psoriasis. However, the precise mechanisms remain unclear. We first obtained bulk transcriptome and single-cell RNA se...

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Bibliographic Details
Main Authors: Jinghua Liu, Nana Luo, Wenyi Ma, Zeyun Qiao, Xiaojing Zhong, Zilin Cheng, Pingsheng Hao, Chengzhi lv
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Ribosome biogenesis
Psoriasis
Immune infiltration
Molecular docking
Biomarkers
Online Access:https://doi.org/10.1038/s41598-025-03833-8
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