Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
A 75-year-old woman presented with progressing pain, cyanosis, and hypaesthesia in her left hand after an intra-articular injection with diazepam into the wrist for osteoarthritis-related pain. Due to an iatrogenic intra-arterial injection, malperfusion of the ulnar digits developed. Angiography rev...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2011/347523 |
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| author | Niklas Iblher Gerd Bjoern Stark Vincenzo Penna |
| author_facet | Niklas Iblher Gerd Bjoern Stark Vincenzo Penna |
| author_sort | Niklas Iblher |
| collection | DOAJ |
| description | A 75-year-old woman presented with progressing pain, cyanosis, and hypaesthesia in her left hand after an intra-articular injection with diazepam into the wrist for osteoarthritis-related pain. Due to an iatrogenic intra-arterial injection, malperfusion of the ulnar digits developed. Angiography revealed blockage of perfusion of the 4th and 5th digits. Despite intra-arterial lysis, heparinisation, and vasodilatation, perfusion could not be reinstalled. Necrosis of the distal phalanges of the 4th and 5th digits developed, which had to be treated with amputation.
The pathomechanism of tissue damage and the treatment options after intra-arterial injections are reviewed and discussed. |
| format | Article |
| id | doaj-art-3a9c94d4db5946af965a15c2d7f9da88 |
| institution | OA Journals |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-3a9c94d4db5946af965a15c2d7f9da882025-08-20T02:07:47ZengWileyCase Reports in Surgery2090-69002090-69192011-01-01201110.1155/2011/347523347523Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the WristNiklas Iblher0Gerd Bjoern Stark1Vincenzo Penna2Department of Plastic and Hand Surgery, University of Freiburg Medical Center, Hugstetter Straße 55, 79106 Freiburg, GermanyDepartment of Plastic and Hand Surgery, University of Freiburg Medical Center, Hugstetter Straße 55, 79106 Freiburg, GermanyDepartment of Plastic and Hand Surgery, University of Freiburg Medical Center, Hugstetter Straße 55, 79106 Freiburg, GermanyA 75-year-old woman presented with progressing pain, cyanosis, and hypaesthesia in her left hand after an intra-articular injection with diazepam into the wrist for osteoarthritis-related pain. Due to an iatrogenic intra-arterial injection, malperfusion of the ulnar digits developed. Angiography revealed blockage of perfusion of the 4th and 5th digits. Despite intra-arterial lysis, heparinisation, and vasodilatation, perfusion could not be reinstalled. Necrosis of the distal phalanges of the 4th and 5th digits developed, which had to be treated with amputation. The pathomechanism of tissue damage and the treatment options after intra-arterial injections are reviewed and discussed.http://dx.doi.org/10.1155/2011/347523 |
| spellingShingle | Niklas Iblher Gerd Bjoern Stark Vincenzo Penna Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist Case Reports in Surgery |
| title | Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist |
| title_full | Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist |
| title_fullStr | Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist |
| title_full_unstemmed | Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist |
| title_short | Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist |
| title_sort | necrosis of the 4th and 5th digits after intra articular injection of diazepam into the wrist |
| url | http://dx.doi.org/10.1155/2011/347523 |
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