DNA damage repair-related methylated genes RRM2 and GAPDH are prognostic biomarkers associated with immunotherapy for lung adenocarcinoma

DNA damage repair-related methylated genes RRM2 and GAPDH are prognostic biomarkers associated with immunotherapy for lung adenocarcinoma

Abstract Research has highlighted the significant role of methylated genes associated with DNA damage repair in pathogenesis of Lung adenocarcinoma (LUAD). However, the potential of DNA damage repair-related gene (DDRG) methylation as a prognostic biomarker remains underexplored. This study aimed to...

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Bibliographic Details
Main Authors: Xinru Mao, Shaban Eljali Saad, Nung Kion Lee, Isabel Lim Fong
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2025-05-01
Series:Genetics and Molecular Biology
Subjects:
Lung adenocarcinoma
DNA methylation
DNA damage repair
prognosis
immunotherapy
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572025000200102&lng=en&tlng=en
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