3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

<b>Background</b>: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease with global implications, necessitating effective management strategies. Dipeptidyl peptidase IV (DPP-4) inhibitors have shown promise as potent agents for T2DM treatment. <b>Methods</b>: This...

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Bibliographic Details
Main Authors:	Tatiana V. Zinevich, Ivan O. Maslov, Olga G. Kirichenko, Sergey V. Shorshnev, Maxim A. Gureev, Fedor M. Dolgushin, Yuri B. Porozov, Vladimir M. Trukhan
Format:	Article
Language:	English
Published:	MDPI AG 2025-04-01
Series:	Pharmaceuticals
Subjects:	type 2 diabetes mellitus DPP-4 inhibitors molecular docking structure–activity relationship stereoisomerism oxadiazoles
Online Access:	https://www.mdpi.com/1424-8247/18/5/642
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