Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery

Introduction Cardiac surgery for older patients, postoperative functional decline and the need for long-term care have received increasing attention as essential outcomes in recent years. Therefore, prevention of functional decline and long-term care dependency after cardiac surgery are important; h...

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Main Authors: Tetsuya Takahashi, Kentaro Iwata, Hidetaka Watanabe, Masayuki Tahara, Masakazu Saitoh, Tomoyuki Morisawa, Akihiro Sakuyama, Koji Sakurada, Yusuke Hanafusa, Yusuke Ochi, Go Takamura, Akira Minei
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Language:English
Published: BMJ Publishing Group 2021-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/12/e054303.full
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author Tetsuya Takahashi
Kentaro Iwata
Hidetaka Watanabe
Masayuki Tahara
Masakazu Saitoh
Tomoyuki Morisawa
Akihiro Sakuyama
Koji Sakurada
Yusuke Hanafusa
Yusuke Ochi
Go Takamura
Akira Minei
author_facet Tetsuya Takahashi
Kentaro Iwata
Hidetaka Watanabe
Masayuki Tahara
Masakazu Saitoh
Tomoyuki Morisawa
Akihiro Sakuyama
Koji Sakurada
Yusuke Hanafusa
Yusuke Ochi
Go Takamura
Akira Minei
author_sort Tetsuya Takahashi
collection DOAJ
description Introduction Cardiac surgery for older patients, postoperative functional decline and the need for long-term care have received increasing attention as essential outcomes in recent years. Therefore, prevention of functional decline and long-term care dependency after cardiac surgery are important; however, our current understanding of postoperative functional trajectory and effects of postoperative regular exercise on long-term functional decline and long-term care dependency is limited. Therefore, we will conduct a multicentre, prospective cohort study to (1) examine the effect of hospital-acquired disability on long-term functional decline and long-term care dependency and (2) investigate the favourable effect of postoperative regular exercise on long-term functional decline and long-term care dependency in older patients after cardiac surgery.Methods and analysis We designed a prospective, multicentre cohort study to enrol older patients aged≥65 years undergoing elective coronary artery bypass graft or valve surgery. We will conduct medical record reviews to collect data on patient demographics, comorbidities, operative details, progression of in-hospital postoperative cardiac rehabilitation and functional trajectory from a few days before cardiac surgery to the day before hospital discharge. They will be followed up for 2 years to obtain information on their health status including functional status, regular exercise and clinical events by mail. Primary endpoints of this study are long-term functional decline and long-term care dependency after cardiac surgery. Secondary endpoints are readmission due to cardiac events or all-cause mortality.Ethics and dissemination The study protocol was approved by the Ethics Committee of the Department of Physical Therapy, Faculty of Health Science, Juntendo University, and of each collaborating hospital. We obtained written informed consent from all study participants after the description of the study procedures. Publication of the study results is anticipated in 2025.
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spelling doaj-art-3a8bf4ded4f940df9002c9adb897dd012025-08-20T02:48:53ZengBMJ Publishing GroupBMJ Open2044-60552021-12-01111210.1136/bmjopen-2021-054303Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgeryTetsuya Takahashi0Kentaro Iwata1Hidetaka Watanabe2Masayuki Tahara3Masakazu Saitoh4Tomoyuki Morisawa5Akihiro Sakuyama6Koji Sakurada7Yusuke Hanafusa8Yusuke Ochi9Go Takamura10Akira Minei11Department of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, JapanDepartment of Rehabilitation, Kobe City Medical Center General Hospital, Kobe, JapanDepartment of Rehabilitation, Juntendo University Hospital, Tokyo, JapanDepartment of Physical Therapy, Higashi Takarazuka Satoh Hospital, Takarazuka, JapanDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, JapanDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, JapanDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, JapanDepartment of Rehabilitation, The Cardiovascular Institute, Tokyo, JapanDepartment of Rehabilitation, Saitama Medical University International Medical Center, Hidaka, JapanDepartment of Rehabilitation, Fukuyama Cardiovascular Hospital, Fukuyama, JapanDepartment of Rehabilitation, Tsuchiya General Hospital, Hiroshima, JapanDepartment of Rehabilitation, Ryukyus University, Nishihara-cho, JapanIntroduction Cardiac surgery for older patients, postoperative functional decline and the need for long-term care have received increasing attention as essential outcomes in recent years. Therefore, prevention of functional decline and long-term care dependency after cardiac surgery are important; however, our current understanding of postoperative functional trajectory and effects of postoperative regular exercise on long-term functional decline and long-term care dependency is limited. Therefore, we will conduct a multicentre, prospective cohort study to (1) examine the effect of hospital-acquired disability on long-term functional decline and long-term care dependency and (2) investigate the favourable effect of postoperative regular exercise on long-term functional decline and long-term care dependency in older patients after cardiac surgery.Methods and analysis We designed a prospective, multicentre cohort study to enrol older patients aged≥65 years undergoing elective coronary artery bypass graft or valve surgery. We will conduct medical record reviews to collect data on patient demographics, comorbidities, operative details, progression of in-hospital postoperative cardiac rehabilitation and functional trajectory from a few days before cardiac surgery to the day before hospital discharge. They will be followed up for 2 years to obtain information on their health status including functional status, regular exercise and clinical events by mail. Primary endpoints of this study are long-term functional decline and long-term care dependency after cardiac surgery. Secondary endpoints are readmission due to cardiac events or all-cause mortality.Ethics and dissemination The study protocol was approved by the Ethics Committee of the Department of Physical Therapy, Faculty of Health Science, Juntendo University, and of each collaborating hospital. We obtained written informed consent from all study participants after the description of the study procedures. Publication of the study results is anticipated in 2025.https://bmjopen.bmj.com/content/11/12/e054303.full
spellingShingle Tetsuya Takahashi
Kentaro Iwata
Hidetaka Watanabe
Masayuki Tahara
Masakazu Saitoh
Tomoyuki Morisawa
Akihiro Sakuyama
Koji Sakurada
Yusuke Hanafusa
Yusuke Ochi
Go Takamura
Akira Minei
Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery
BMJ Open
title Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery
title_full Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery
title_fullStr Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery
title_full_unstemmed Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery
title_short Protocol for a multicentre, prospective observational cohort study in Japan: association among hospital-acquired disability, regular exercise and long-term care dependency in older patients after cardiac surgery
title_sort protocol for a multicentre prospective observational cohort study in japan association among hospital acquired disability regular exercise and long term care dependency in older patients after cardiac surgery
url https://bmjopen.bmj.com/content/11/12/e054303.full
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