Incidence of and risk factors for mortality in children with mushroom poisoning
Abstract Objective We aimed to evaluate the incidence of and risk factors for mortality in children with mushroom poisoning. Methods Sixty-seven children with mushroom poisoning who were hospitalized at the Children’s Hospital of Chongqing Medical University were retrospectively enrolled. The clinic...
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BMC
2025-06-01
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| Series: | International Journal of Emergency Medicine |
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| Online Access: | https://doi.org/10.1186/s12245-025-00906-3 |
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| author | Jie Cheng Ya Liu Shaojun Li Kaibin Pu Junming Huo Liping Tan |
| author_facet | Jie Cheng Ya Liu Shaojun Li Kaibin Pu Junming Huo Liping Tan |
| author_sort | Jie Cheng |
| collection | DOAJ |
| description | Abstract Objective We aimed to evaluate the incidence of and risk factors for mortality in children with mushroom poisoning. Methods Sixty-seven children with mushroom poisoning who were hospitalized at the Children’s Hospital of Chongqing Medical University were retrospectively enrolled. The clinical characteristics of the children in the surviving and non-surviving groups were compared. Variables with a P value < 0.1 in the univariate logistic regression analysis were included in the multivariate logistic regression analysis. A receiver operating characteristic (ROC) curve was generated to determine the optimal cutoff point. Results The mortality rate of children with mushroom poisoning was 23.88% (16/67), and the incidence of death during hospitalization was 35.02 per 1,000 person-days. The median pediatric sequential organ failure assessment (pSOFA) score was 1.00 (interquartile range [IQR] 0.00–3.00). Logistic regression analysis revealed that the pSOFA score was independently associated with mortality (odds ratio [OR] 4.92, 95% confidence interval [CI] 1.59–62.21; P = 0.040). The optimal cutoff point of the pSOFA score for predicting mortality was 2.00, with an area under the curve (AUC) of 0.84 (95% CI 0.71–0.88, P < 0.001*). Conclusions In this study, the incidence of death among children with mushroom poisoning was retrospectively evaluated. The pSOFA score may serve as a good prognostic indicator in children with mushroom poisoning, and children with a pSOFA score ≥ 2 have a significantly increased risk of mortality. |
| format | Article |
| id | doaj-art-3a8b7d57d36e408487edd086e6cd4ad8 |
| institution | OA Journals |
| issn | 1865-1380 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | BMC |
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| series | International Journal of Emergency Medicine |
| spelling | doaj-art-3a8b7d57d36e408487edd086e6cd4ad82025-08-20T02:36:50ZengBMCInternational Journal of Emergency Medicine1865-13802025-06-011811810.1186/s12245-025-00906-3Incidence of and risk factors for mortality in children with mushroom poisoningJie Cheng0Ya Liu1Shaojun Li2Kaibin Pu3Junming Huo4Liping Tan5Department of Emergency, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical UniversityDepartment of Pediatrics, Chongqing Youyoubaobei Women and Children’s HospitalDepartment of Emergency, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical UniversityDepartment of Emergency, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical UniversityDepartment of Critical Care Medicine, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical UniversityDepartment of Emergency, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical UniversityAbstract Objective We aimed to evaluate the incidence of and risk factors for mortality in children with mushroom poisoning. Methods Sixty-seven children with mushroom poisoning who were hospitalized at the Children’s Hospital of Chongqing Medical University were retrospectively enrolled. The clinical characteristics of the children in the surviving and non-surviving groups were compared. Variables with a P value < 0.1 in the univariate logistic regression analysis were included in the multivariate logistic regression analysis. A receiver operating characteristic (ROC) curve was generated to determine the optimal cutoff point. Results The mortality rate of children with mushroom poisoning was 23.88% (16/67), and the incidence of death during hospitalization was 35.02 per 1,000 person-days. The median pediatric sequential organ failure assessment (pSOFA) score was 1.00 (interquartile range [IQR] 0.00–3.00). Logistic regression analysis revealed that the pSOFA score was independently associated with mortality (odds ratio [OR] 4.92, 95% confidence interval [CI] 1.59–62.21; P = 0.040). The optimal cutoff point of the pSOFA score for predicting mortality was 2.00, with an area under the curve (AUC) of 0.84 (95% CI 0.71–0.88, P < 0.001*). Conclusions In this study, the incidence of death among children with mushroom poisoning was retrospectively evaluated. The pSOFA score may serve as a good prognostic indicator in children with mushroom poisoning, and children with a pSOFA score ≥ 2 have a significantly increased risk of mortality.https://doi.org/10.1186/s12245-025-00906-3IncidenceRisk factorsMushroom poisoningMortalityChildren |
| spellingShingle | Jie Cheng Ya Liu Shaojun Li Kaibin Pu Junming Huo Liping Tan Incidence of and risk factors for mortality in children with mushroom poisoning International Journal of Emergency Medicine Incidence Risk factors Mushroom poisoning Mortality Children |
| title | Incidence of and risk factors for mortality in children with mushroom poisoning |
| title_full | Incidence of and risk factors for mortality in children with mushroom poisoning |
| title_fullStr | Incidence of and risk factors for mortality in children with mushroom poisoning |
| title_full_unstemmed | Incidence of and risk factors for mortality in children with mushroom poisoning |
| title_short | Incidence of and risk factors for mortality in children with mushroom poisoning |
| title_sort | incidence of and risk factors for mortality in children with mushroom poisoning |
| topic | Incidence Risk factors Mushroom poisoning Mortality Children |
| url | https://doi.org/10.1186/s12245-025-00906-3 |
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