Generation of Site‐Specifically Labeled Affinity Reagents via Use of a Self‐Labeling Single Domain Antibody

Generation of Site‐Specifically Labeled Affinity Reagents via Use of a Self‐Labeling Single Domain Antibody

Abstract Several chemical and enzymatic methods have been used to link antibodies to moieties that facilitate visualization of cognate targets. Emerging evidence suggests that the extent of labeling, dictated by the type of chemistry used, has a substantial impact on performance, especially in the c...

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Bibliographic Details
Main Authors: Stanley Fayn, Swarnali Roy, Chino C. Cabalteja, Woonghee Lee, Hima Makala, Kwamena Baidoo, Divya Nambiar, Julia Sheehan‐Klenk, Joon‐Yong Chung, Jesse Buffington, Mitchell Ho, Freddy E. Escorcia, Ross W. Cheloha
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
antibodies
conjugation
molecular imaging
nanobody
peptide
Online Access:https://doi.org/10.1002/advs.202417160
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