Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats

Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats

Abstract Painful diabetic neuropathy (PDN) is one of the most common complications of diabetes. Recent studies suggested that gut microbiota dysbiosis contributes to the development of PDN, but underlying mechanisms remain elusive. In this study, we found decreased probiotics generating bacteria suc...

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Main Authors: Ye Jiang, Jing Yang, Min Wei, Jiayin Shou, Shixiong Shen, Zhuoying Yu, Zixian Zhang, Jie Cai, Yanhan Lyu, Dongsheng Yang, Yongzheng Han, Jinpiao Zhu, Zhigang Liu, Daqing Ma, Guo-gang Xing, Min Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Neuroinflammation
Subjects:
Painful diabetic neuropathy
Microbiota–gut–nerve axis
Probiotics
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-025-03352-3
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