Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia
Hemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one’s own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggere...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2014/287479 |
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| author | Nura El-Haj Wilson I. Gonsalves Vinay Gupta Jacob P. Smeltzer Sameer A. Parikh Preet P. Singh Naseema Gangat |
| author_facet | Nura El-Haj Wilson I. Gonsalves Vinay Gupta Jacob P. Smeltzer Sameer A. Parikh Preet P. Singh Naseema Gangat |
| author_sort | Nura El-Haj |
| collection | DOAJ |
| description | Hemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one’s own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggered by infectious agents, malignancy, or drugs. We describe the first case of a CLL patient presenting with HPS due to acquisition of EBV-related large cell lymphoma in the setting of profound immunodeficiency. |
| format | Article |
| id | doaj-art-3a7d9ac1c7964c54aaaedbcd734d63a7 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-3a7d9ac1c7964c54aaaedbcd734d63a72025-02-03T05:48:12ZengWileyCase Reports in Hematology2090-65602090-65792014-01-01201410.1155/2014/287479287479Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic LeukemiaNura El-Haj0Wilson I. Gonsalves1Vinay Gupta2Jacob P. Smeltzer3Sameer A. Parikh4Preet P. Singh5Naseema Gangat6Trinity College, Dublin, IrelandDepartment of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USADepartment of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USADepartment of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USADepartment of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USADepartment of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USADepartment of Hematology, Mayo Clinic Rochester, 200 1st Street SW, Rochester, MN 55905, USAHemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one’s own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggered by infectious agents, malignancy, or drugs. We describe the first case of a CLL patient presenting with HPS due to acquisition of EBV-related large cell lymphoma in the setting of profound immunodeficiency.http://dx.doi.org/10.1155/2014/287479 |
| spellingShingle | Nura El-Haj Wilson I. Gonsalves Vinay Gupta Jacob P. Smeltzer Sameer A. Parikh Preet P. Singh Naseema Gangat Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia Case Reports in Hematology |
| title | Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia |
| title_full | Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia |
| title_fullStr | Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia |
| title_full_unstemmed | Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia |
| title_short | Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia |
| title_sort | secondary hemophagocytic syndrome associated with richter s transformation in chronic lymphocytic leukemia |
| url | http://dx.doi.org/10.1155/2014/287479 |
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