Does Birth Weight affect on Coagulation Profile?
There are limited studies assessing haemostatic factors in relation to birth weight. Our study aimed to assess the differences in values of coagulation factors between 3 groups of neonates with different birth weight. A cross-sectional study enrolling 53 healthy neonates compared coagulation factor...
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1772 |
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| author | alireza abdollahi sara sheikhbahaei |
| author_facet | alireza abdollahi sara sheikhbahaei |
| author_sort | alireza abdollahi |
| collection | DOAJ |
| description | There are limited studies assessing haemostatic factors in relation to birth weight. Our study aimed to assess the differences in values of coagulation factors between 3 groups of neonates with different birth weight.
A cross-sectional study enrolling 53 healthy neonates compared coagulation factors according to the birth weight for their gestational age. For this, PT, APTT, INR, TT, and levels of fibrinogen, anti thrombin III, protein S and protein C were compared between neonates divided into 3 different groups including small, appropriate, and large for gestational age.
There was statistically significant difference in levels of protein S (p<0.0001) and values of APTT (p=0.01) between 3 different groups. Other coagulation factors however, did not represent an explainable or significant pattern (p>0.05). Protein S concentration, directly (B: 0.76, PV<0.0001), and APTT, inversely (B: - 0.33, PV=0.01), associated with birth weight after adjusting for gestational age and sex .
Despite decreased APTT from SGA, to AGA, and LGA neonates, level of protein S increase directly with birth weight. However, no other coagulation factors revealed an explainable pattern in relation to either state of SGA, AGA, or LGA. |
| format | Article |
| id | doaj-art-3a7d449e2fd6416ebf1e6d6c8ef6c54f |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-3a7d449e2fd6416ebf1e6d6c8ef6c54f2025-01-02T06:31:56ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011Does Birth Weight affect on Coagulation Profile?alireza abdollahi0sara sheikhbahaei1tehran university of medical sciencesDivision of Pathology, Imam Hospitals Complex, Tehran University of Medical Science, Tehran, IranThere are limited studies assessing haemostatic factors in relation to birth weight. Our study aimed to assess the differences in values of coagulation factors between 3 groups of neonates with different birth weight. A cross-sectional study enrolling 53 healthy neonates compared coagulation factors according to the birth weight for their gestational age. For this, PT, APTT, INR, TT, and levels of fibrinogen, anti thrombin III, protein S and protein C were compared between neonates divided into 3 different groups including small, appropriate, and large for gestational age. There was statistically significant difference in levels of protein S (p<0.0001) and values of APTT (p=0.01) between 3 different groups. Other coagulation factors however, did not represent an explainable or significant pattern (p>0.05). Protein S concentration, directly (B: 0.76, PV<0.0001), and APTT, inversely (B: - 0.33, PV=0.01), associated with birth weight after adjusting for gestational age and sex . Despite decreased APTT from SGA, to AGA, and LGA neonates, level of protein S increase directly with birth weight. However, no other coagulation factors revealed an explainable pattern in relation to either state of SGA, AGA, or LGA.https://mjhid.org/index.php/mjhid/article/view/1772Birth WeightNeonateCoagulation |
| spellingShingle | alireza abdollahi sara sheikhbahaei Does Birth Weight affect on Coagulation Profile? Mediterranean Journal of Hematology and Infectious Diseases Birth Weight Neonate Coagulation |
| title | Does Birth Weight affect on Coagulation Profile? |
| title_full | Does Birth Weight affect on Coagulation Profile? |
| title_fullStr | Does Birth Weight affect on Coagulation Profile? |
| title_full_unstemmed | Does Birth Weight affect on Coagulation Profile? |
| title_short | Does Birth Weight affect on Coagulation Profile? |
| title_sort | does birth weight affect on coagulation profile |
| topic | Birth Weight Neonate Coagulation |
| url | https://mjhid.org/index.php/mjhid/article/view/1772 |
| work_keys_str_mv | AT alirezaabdollahi doesbirthweightaffectoncoagulationprofile AT sarasheikhbahaei doesbirthweightaffectoncoagulationprofile |