Physiological indices for the categorization of Mibyeong severity
Background: Individuals with Mibyeong are difficult to identify. Although extensive research has attempted to introduce an easy and clear method for Mibyeong diagnosis, the indices used to categorize Mibyeong severity are unclear. We hypothesized that individuals with severe Mibyeong have reduced ph...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-03-01
|
| Series: | Integrative Medicine Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422016301913 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850217631263490048 |
|---|---|
| author | Kyung Eun Lee Joong Jae Kim Hee-Jeong Jin Siwoo Lee Eun Bo Shim |
| author_facet | Kyung Eun Lee Joong Jae Kim Hee-Jeong Jin Siwoo Lee Eun Bo Shim |
| author_sort | Kyung Eun Lee |
| collection | DOAJ |
| description | Background: Individuals with Mibyeong are difficult to identify. Although extensive research has attempted to introduce an easy and clear method for Mibyeong diagnosis, the indices used to categorize Mibyeong severity are unclear. We hypothesized that individuals with severe Mibyeong have reduced physiological function, thus activating homeostatic regulatory functions and inducing alterations in vascular resistance and capacitance.
Methods: Novel indices used to categorize Mibyeong severity based on the cardiovascular system model are described. We analyzed resistance and capacitance values using a simple cardiovascular system model optimally satisfying the measured systolic and diastolic pressures, heart rate, and age.
Results: Clinical data from 509 individuals were examined to test our hypothesis. A statistical analysis revealed that the vascular resistance was lower in individuals with severe Mibyeong symptoms and decreased with increasing Mibyeong severity, whereas the vascular capacitance showed an opposite trend.
Conclusion: We derived indices to categorize Mibyeong severity and tested 509 individuals. An epidemiological analysis revealed that the vascular resistance decreased while the capacitance increased with increasing Mibyeong severity, indicating the validity of the values as Mibyeong indices. |
| format | Article |
| id | doaj-art-3a654e627a1840e6af78c231cf370521 |
| institution | OA Journals |
| issn | 2213-4220 |
| language | English |
| publishDate | 2017-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj-art-3a654e627a1840e6af78c231cf3705212025-08-20T02:08:00ZengElsevierIntegrative Medicine Research2213-42202017-03-0161889210.1016/j.imr.2017.01.005Physiological indices for the categorization of Mibyeong severityKyung Eun Lee0Joong Jae Kim1Hee-Jeong Jin2Siwoo Lee3Eun Bo Shim4Department of Mechanical and Biomedical Engineering, Kangwon National University, Chuncheon, KoreaDepartment of Mechanical and Biomedical Engineering, Kangwon National University, Chuncheon, KoreaMibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, KoreaMibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, KoreaDepartment of Mechanical and Biomedical Engineering, Kangwon National University, Chuncheon, KoreaBackground: Individuals with Mibyeong are difficult to identify. Although extensive research has attempted to introduce an easy and clear method for Mibyeong diagnosis, the indices used to categorize Mibyeong severity are unclear. We hypothesized that individuals with severe Mibyeong have reduced physiological function, thus activating homeostatic regulatory functions and inducing alterations in vascular resistance and capacitance. Methods: Novel indices used to categorize Mibyeong severity based on the cardiovascular system model are described. We analyzed resistance and capacitance values using a simple cardiovascular system model optimally satisfying the measured systolic and diastolic pressures, heart rate, and age. Results: Clinical data from 509 individuals were examined to test our hypothesis. A statistical analysis revealed that the vascular resistance was lower in individuals with severe Mibyeong symptoms and decreased with increasing Mibyeong severity, whereas the vascular capacitance showed an opposite trend. Conclusion: We derived indices to categorize Mibyeong severity and tested 509 individuals. An epidemiological analysis revealed that the vascular resistance decreased while the capacitance increased with increasing Mibyeong severity, indicating the validity of the values as Mibyeong indices.http://www.sciencedirect.com/science/article/pii/S2213422016301913cardiovascular system modelcategorizationMibyeong indexresistance and capacitance, |
| spellingShingle | Kyung Eun Lee Joong Jae Kim Hee-Jeong Jin Siwoo Lee Eun Bo Shim Physiological indices for the categorization of Mibyeong severity Integrative Medicine Research cardiovascular system model categorization Mibyeong index resistance and capacitance, |
| title | Physiological indices for the categorization of Mibyeong severity |
| title_full | Physiological indices for the categorization of Mibyeong severity |
| title_fullStr | Physiological indices for the categorization of Mibyeong severity |
| title_full_unstemmed | Physiological indices for the categorization of Mibyeong severity |
| title_short | Physiological indices for the categorization of Mibyeong severity |
| title_sort | physiological indices for the categorization of mibyeong severity |
| topic | cardiovascular system model categorization Mibyeong index resistance and capacitance, |
| url | http://www.sciencedirect.com/science/article/pii/S2213422016301913 |
| work_keys_str_mv | AT kyungeunlee physiologicalindicesforthecategorizationofmibyeongseverity AT joongjaekim physiologicalindicesforthecategorizationofmibyeongseverity AT heejeongjin physiologicalindicesforthecategorizationofmibyeongseverity AT siwoolee physiologicalindicesforthecategorizationofmibyeongseverity AT eunboshim physiologicalindicesforthecategorizationofmibyeongseverity |