Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition
This case study delves into the link, between exposure to Bisphenol A (BPA) and kidney issues filling a gap in human focused research found in studies. The individual, a 72-year man with a history of BPA exposure in a plastics manufacturing facility experienced a gradual decline in kidney function o...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Pathology and Oncology Research |
| Subjects: | |
| Online Access: | https://www.por-journal.com/articles/10.3389/pore.2025.1612046/full |
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| author | László Bidiga Tamás Csonka Gábor Méhes Csilla Markóth Dávid Hutkai János Mátyus |
| author_facet | László Bidiga Tamás Csonka Gábor Méhes Csilla Markóth Dávid Hutkai János Mátyus |
| author_sort | László Bidiga |
| collection | DOAJ |
| description | This case study delves into the link, between exposure to Bisphenol A (BPA) and kidney issues filling a gap in human focused research found in studies. The individual, a 72-year man with a history of BPA exposure in a plastics manufacturing facility experienced a gradual decline in kidney function over 18 months. Medical tests showed kidney disease with a buildup of lipofuscin in renal tubular cells upon examination. This discovery suggests a connection between BPA exposure and kidney damage underscoring the need for investigation. The lack of human based evidence highlights the importance of research to understand the toxic effects of BPA on the kidneys. In addition, to its implications this case emphasizes the importance of improving safety protocols and raising awareness among healthcare professionals in relevant work environments to reduce potential health risks associated with BPA exposure. |
| format | Article |
| id | doaj-art-3a5bbef3459444d89e132e04e5e2fee2 |
| institution | Kabale University |
| issn | 1532-2807 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Pathology and Oncology Research |
| spelling | doaj-art-3a5bbef3459444d89e132e04e5e2fee22025-08-20T03:33:03ZengFrontiers Media S.A.Pathology and Oncology Research1532-28072025-07-013110.3389/pore.2025.16120461612046Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A expositionLászló Bidiga0Tamás Csonka1Gábor Méhes2Csilla Markóth3Dávid Hutkai4János Mátyus5Department of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, HungaryDepartment of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, HungaryDepartment of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, HungaryDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, HungaryDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, HungaryDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, HungaryThis case study delves into the link, between exposure to Bisphenol A (BPA) and kidney issues filling a gap in human focused research found in studies. The individual, a 72-year man with a history of BPA exposure in a plastics manufacturing facility experienced a gradual decline in kidney function over 18 months. Medical tests showed kidney disease with a buildup of lipofuscin in renal tubular cells upon examination. This discovery suggests a connection between BPA exposure and kidney damage underscoring the need for investigation. The lack of human based evidence highlights the importance of research to understand the toxic effects of BPA on the kidneys. In addition, to its implications this case emphasizes the importance of improving safety protocols and raising awareness among healthcare professionals in relevant work environments to reduce potential health risks associated with BPA exposure.https://www.por-journal.com/articles/10.3389/pore.2025.1612046/fullbisphenol A (BPA) exposurenephrotoxicitychronic kidney diseaselipofuscin accumulationworkplace safety |
| spellingShingle | László Bidiga Tamás Csonka Gábor Méhes Csilla Markóth Dávid Hutkai János Mátyus Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition Pathology and Oncology Research bisphenol A (BPA) exposure nephrotoxicity chronic kidney disease lipofuscin accumulation workplace safety |
| title | Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition |
| title_full | Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition |
| title_fullStr | Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition |
| title_full_unstemmed | Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition |
| title_short | Case Report: Toxic tubulointerstitial nephropathy with lipofuscin deposition – the potential cause of occupational Bisphenol-A exposition |
| title_sort | case report toxic tubulointerstitial nephropathy with lipofuscin deposition the potential cause of occupational bisphenol a exposition |
| topic | bisphenol A (BPA) exposure nephrotoxicity chronic kidney disease lipofuscin accumulation workplace safety |
| url | https://www.por-journal.com/articles/10.3389/pore.2025.1612046/full |
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