Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses

Abstract Wheat (Triticum aestivum L.) is a vital global crop; however, its productivity is facing increasing threats from soil salinity, which affects a significant portion of arable land worldwide. This study investigates the potential of synthetic Strigolactone (GR24) to enhance salinity tolerance...

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Main Authors: Parisa Jariani, Manijeh Sabokdast, Fatemeh Rajabi, Mohammad Reza Naghavi, Beata Dedicova
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-08670-3
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author Parisa Jariani
Manijeh Sabokdast
Fatemeh Rajabi
Mohammad Reza Naghavi
Beata Dedicova
author_facet Parisa Jariani
Manijeh Sabokdast
Fatemeh Rajabi
Mohammad Reza Naghavi
Beata Dedicova
author_sort Parisa Jariani
collection DOAJ
description Abstract Wheat (Triticum aestivum L.) is a vital global crop; however, its productivity is facing increasing threats from soil salinity, which affects a significant portion of arable land worldwide. This study investigates the potential of synthetic Strigolactone (GR24) to enhance salinity tolerance in wheat by examining its effects on antioxidant enzyme activity, ion homeostasis, and gene expression. Three wheat cultivars with varying salinity resistance (Sistan, Pishtaz, and Tajen) were treated with 10 µM GR24 under two salinity levels (5 and 15 dS/m). Salinity stress was applied from the 3–4 leaf stage to tillering. GR24 significantly enhanced the activities of antioxidant enzymes such as ascorbate peroxidase, catalase, and polyphenol oxidase while reducing guaiacol peroxidase activity. Proline content, potassium levels, and concentrations of chlorophyll and carotenoids were markedly increased, while sodium ion accumulation and indicators of oxidative damage (malondialdehyde, hydrogen peroxide, and electrolyte leakage) were reduced. These effects improved leaf water retention and overall stress resilience. Furthermore, polyphenol oxidase activity highlighted a potential novel pathway of Strigolactone action involving interactions with other phytohormones. Gene expression analysis via real-time PCR revealed that GR24 modulates the transcription of stress-responsive genes, including antiporter genes crucial for maintaining Na+/K + homeostasis and reducing ion toxicity. Among the cultivars, Sistan and Tajen exhibited the most robust responses at a salinity level of 15 dS/m. These findings underscore the potential of GR24 as a promising tool for enhancing wheat performance in saline environments.
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spelling doaj-art-3a4e768446b14ae680e88de5cd8d3e9d2025-08-20T03:05:26ZengNature PortfolioScientific Reports2045-23222025-07-0115112310.1038/s41598-025-08670-3Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responsesParisa Jariani0Manijeh Sabokdast1Fatemeh Rajabi2Mohammad Reza Naghavi3Beata Dedicova4Department of Agronomy and Plant Breeding, College of Agriculture and Natural Resources, University of TehranDepartment of Agronomy and Plant Breeding, College of Agriculture and Natural Resources, University of TehranDepartment of Agronomy and Plant Breeding, College of Agriculture and Natural Resources, University of TehranDepartment of Agronomy and Plant Breeding, College of Agriculture and Natural Resources, University of TehranDepartment of Plant Breeding, Swedish University of Agricultural Sciences (SLU)Abstract Wheat (Triticum aestivum L.) is a vital global crop; however, its productivity is facing increasing threats from soil salinity, which affects a significant portion of arable land worldwide. This study investigates the potential of synthetic Strigolactone (GR24) to enhance salinity tolerance in wheat by examining its effects on antioxidant enzyme activity, ion homeostasis, and gene expression. Three wheat cultivars with varying salinity resistance (Sistan, Pishtaz, and Tajen) were treated with 10 µM GR24 under two salinity levels (5 and 15 dS/m). Salinity stress was applied from the 3–4 leaf stage to tillering. GR24 significantly enhanced the activities of antioxidant enzymes such as ascorbate peroxidase, catalase, and polyphenol oxidase while reducing guaiacol peroxidase activity. Proline content, potassium levels, and concentrations of chlorophyll and carotenoids were markedly increased, while sodium ion accumulation and indicators of oxidative damage (malondialdehyde, hydrogen peroxide, and electrolyte leakage) were reduced. These effects improved leaf water retention and overall stress resilience. Furthermore, polyphenol oxidase activity highlighted a potential novel pathway of Strigolactone action involving interactions with other phytohormones. Gene expression analysis via real-time PCR revealed that GR24 modulates the transcription of stress-responsive genes, including antiporter genes crucial for maintaining Na+/K + homeostasis and reducing ion toxicity. Among the cultivars, Sistan and Tajen exhibited the most robust responses at a salinity level of 15 dS/m. These findings underscore the potential of GR24 as a promising tool for enhancing wheat performance in saline environments.https://doi.org/10.1038/s41598-025-08670-3Abiotic stressAntioxidant enzymesSalinity toleranceStrigolactones (GR24)Triticum aestivum L
spellingShingle Parisa Jariani
Manijeh Sabokdast
Fatemeh Rajabi
Mohammad Reza Naghavi
Beata Dedicova
Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses
Scientific Reports
Abiotic stress
Antioxidant enzymes
Salinity tolerance
Strigolactones (GR24)
Triticum aestivum L
title Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses
title_full Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses
title_fullStr Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses
title_full_unstemmed Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses
title_short Enhancing salinity tolerance in wheat: the role of synthetic Strigolactone (GR24) in modulating antioxidant enzyme activities, ion channels, and related gene expression in stress responses
title_sort enhancing salinity tolerance in wheat the role of synthetic strigolactone gr24 in modulating antioxidant enzyme activities ion channels and related gene expression in stress responses
topic Abiotic stress
Antioxidant enzymes
Salinity tolerance
Strigolactones (GR24)
Triticum aestivum L
url https://doi.org/10.1038/s41598-025-08670-3
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