Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy

Parkinson’s disease (PD), a neurodegenerative disorder, is the second most common neurological illness in United States. Neurologically, it is characterized by the selective degeneration of a unique population of cells, the nigrostriatal dopamine neurons. The current treatment is symptomatic and mai...

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Main Authors: Mariana Babayeva, Haregewein Assefa, Paramita Basu, Sanjeda Chumki, Zvi Loewy
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2016/1279042
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author Mariana Babayeva
Haregewein Assefa
Paramita Basu
Sanjeda Chumki
Zvi Loewy
author_facet Mariana Babayeva
Haregewein Assefa
Paramita Basu
Sanjeda Chumki
Zvi Loewy
author_sort Mariana Babayeva
collection DOAJ
description Parkinson’s disease (PD), a neurodegenerative disorder, is the second most common neurological illness in United States. Neurologically, it is characterized by the selective degeneration of a unique population of cells, the nigrostriatal dopamine neurons. The current treatment is symptomatic and mainly involves replacement of dopamine deficiency. This therapy improves only motor symptoms of Parkinson’s disease and is associated with a number of adverse effects including dyskinesia. Therefore, there is unmet need for more comprehensive approach in the management of PD. Cannabis and related compounds have created significant research interest as a promising therapy in neurodegenerative and movement disorders. In this review we examine the potential benefits of medical marijuana and related compounds in the treatment of both motor and nonmotor symptoms as well as in slowing the progression of the disease. The potential for cannabis to enhance the quality of life of Parkinson’s patients is explored.
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issn 2090-8083
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publishDate 2016-01-01
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series Parkinson's Disease
spelling doaj-art-3a4cb1222bd44d21982db46ed41f87182025-02-03T01:07:52ZengWileyParkinson's Disease2090-80832042-00802016-01-01201610.1155/2016/12790421279042Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease TherapyMariana Babayeva0Haregewein Assefa1Paramita Basu2Sanjeda Chumki3Zvi Loewy4Touro College of Pharmacy, 230 West 125th Street, Room 530, New York, NY 10027, USATouro College of Pharmacy, 230 West 125th Street, Room 530, New York, NY 10027, USATouro College of Pharmacy, 230 West 125th Street, Room 530, New York, NY 10027, USATouro College of Pharmacy, 230 West 125th Street, Room 530, New York, NY 10027, USATouro College of Pharmacy, 230 West 125th Street, Room 530, New York, NY 10027, USAParkinson’s disease (PD), a neurodegenerative disorder, is the second most common neurological illness in United States. Neurologically, it is characterized by the selective degeneration of a unique population of cells, the nigrostriatal dopamine neurons. The current treatment is symptomatic and mainly involves replacement of dopamine deficiency. This therapy improves only motor symptoms of Parkinson’s disease and is associated with a number of adverse effects including dyskinesia. Therefore, there is unmet need for more comprehensive approach in the management of PD. Cannabis and related compounds have created significant research interest as a promising therapy in neurodegenerative and movement disorders. In this review we examine the potential benefits of medical marijuana and related compounds in the treatment of both motor and nonmotor symptoms as well as in slowing the progression of the disease. The potential for cannabis to enhance the quality of life of Parkinson’s patients is explored.http://dx.doi.org/10.1155/2016/1279042
spellingShingle Mariana Babayeva
Haregewein Assefa
Paramita Basu
Sanjeda Chumki
Zvi Loewy
Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy
Parkinson's Disease
title Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy
title_full Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy
title_fullStr Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy
title_full_unstemmed Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy
title_short Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy
title_sort marijuana compounds a nonconventional approach to parkinson s disease therapy
url http://dx.doi.org/10.1155/2016/1279042
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