Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis

We report an 83-year-old immune-competent female with unilateral endophthalmitis extraordinarily caused by cytomegalovirus (CMV). Since she was suspected of suffering possible bacterial endophthalmitis, she was referred to our hospital. At the first visit, hypopyon in the anterior chamber and the op...

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Main Authors: Atsushi Yoshida, Hiroto Obata, Hidetoshi Kawashima
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2015/489813
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author Atsushi Yoshida
Hiroto Obata
Hidetoshi Kawashima
author_facet Atsushi Yoshida
Hiroto Obata
Hidetoshi Kawashima
author_sort Atsushi Yoshida
collection DOAJ
description We report an 83-year-old immune-competent female with unilateral endophthalmitis extraordinarily caused by cytomegalovirus (CMV). Since she was suspected of suffering possible bacterial endophthalmitis, she was referred to our hospital. At the first visit, hypopyon in the anterior chamber and the opacity of vitreous body were observed in the left eye. The best-corrected visual acuity (BCVA) of the left eye was counting fingers and the intraocular pressure (IOP) was 20 mmHg. Bacterial and fungus culture of the aqueous humor revealed no infection. However, the density of corneal endothelial cell was less than the measurable range and CMV was detected by PCR of the aqueous humor. She was immune-competent and the data indicated neither systemic infections nor diseases. Systemic valganciclovir and corticosteroid were administered. After that, hypopyon in the anterior chamber and the opacity of vitreous body of the left eye were improved, and the BCVA of the left eye was 20/200 one year after the first visit. However, the inflammation of the anterior chamber recurred accompanied by elevated IOP after the discontinuance of administering valganciclovir. CMV-induced uveitis accompanied with hypopyon is quite rare. Therefore, it can be easily misdiagnosed as bacterial endophthalmitis.
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spelling doaj-art-3a3fe2f892ab4bc484d372bf324a5cb62025-02-03T01:07:15ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302015-01-01201510.1155/2015/489813489813Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial EndophthalmitisAtsushi Yoshida0Hiroto Obata1Hidetoshi Kawashima2Department of Ophthalmology, Jichi Medical University, 3311-1 Yakushiji, Tochigi, Shimotsuke 329-0498, JapanDepartment of Ophthalmology, Jichi Medical University, 3311-1 Yakushiji, Tochigi, Shimotsuke 329-0498, JapanDepartment of Ophthalmology, Jichi Medical University, 3311-1 Yakushiji, Tochigi, Shimotsuke 329-0498, JapanWe report an 83-year-old immune-competent female with unilateral endophthalmitis extraordinarily caused by cytomegalovirus (CMV). Since she was suspected of suffering possible bacterial endophthalmitis, she was referred to our hospital. At the first visit, hypopyon in the anterior chamber and the opacity of vitreous body were observed in the left eye. The best-corrected visual acuity (BCVA) of the left eye was counting fingers and the intraocular pressure (IOP) was 20 mmHg. Bacterial and fungus culture of the aqueous humor revealed no infection. However, the density of corneal endothelial cell was less than the measurable range and CMV was detected by PCR of the aqueous humor. She was immune-competent and the data indicated neither systemic infections nor diseases. Systemic valganciclovir and corticosteroid were administered. After that, hypopyon in the anterior chamber and the opacity of vitreous body of the left eye were improved, and the BCVA of the left eye was 20/200 one year after the first visit. However, the inflammation of the anterior chamber recurred accompanied by elevated IOP after the discontinuance of administering valganciclovir. CMV-induced uveitis accompanied with hypopyon is quite rare. Therefore, it can be easily misdiagnosed as bacterial endophthalmitis.http://dx.doi.org/10.1155/2015/489813
spellingShingle Atsushi Yoshida
Hiroto Obata
Hidetoshi Kawashima
Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
Case Reports in Ophthalmological Medicine
title Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
title_full Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
title_fullStr Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
title_full_unstemmed Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
title_short Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis
title_sort cytomegalovirus uveitis with hypopyon mimicking bacterial endophthalmitis
url http://dx.doi.org/10.1155/2015/489813
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AT hirotoobata cytomegalovirusuveitiswithhypopyonmimickingbacterialendophthalmitis
AT hidetoshikawashima cytomegalovirusuveitiswithhypopyonmimickingbacterialendophthalmitis