Immunogenicity and safety of 1 versus 2 doses of quadrivalent-inactivated influenza vaccine in children aged 3–8 years with or without previous influenza vaccination histories

Immunogenicity and safety of 1 versus 2 doses of quadrivalent-inactivated influenza vaccine in children aged 3–8 years with or without previous influenza vaccination histories

This study assessed the immunogenicity and safety of a quadrivalent influenza split-virion vaccine (IIV4) in children with and without prior influenza vaccination. An open-label, phase IV clinical trial was conducted in healthy children aged 3–8 years in Pizhou, Jiangsu Province, China. Children wit...

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Bibliographic Details
Main Authors: Feng Wen, Sheng Liu, Li Zhou, Yinbiao Zhu, Wenjuan Wang, Mingwei Wei, Xinglong Xu, Yan Liu, Qi Shuai, Jun Yu, Pengfei Jing, Jingxin Li, Fengcai Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Inactivated influenza vaccine
immunogenicity
safety
previous influenza vaccination
1 versus 2 doses
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2468074
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