Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit

Background: Ventilator-Associated Pneumonia (VAP) is one of the most common nosocomial infections that occurs after intubation in patients with mechanical ventilation. Methods: This cross-sectional descriptive study was conducted in a group of patients admitted to the ICU with a sample size of 120...

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Main Authors: Parisa Delkash, Soheila Sadeghi, Seyed Amir Sheikholeslami, Mahmoud Dehghani-Ghorbi, Amir Behnam Kharazmi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-02-01
Series:Archives of Anesthesia and Critical Care
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Online Access:https://aacc.tums.ac.ir/index.php/aacc/article/view/1139
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author Parisa Delkash
Soheila Sadeghi
Seyed Amir Sheikholeslami
Mahmoud Dehghani-Ghorbi
Amir Behnam Kharazmi
author_facet Parisa Delkash
Soheila Sadeghi
Seyed Amir Sheikholeslami
Mahmoud Dehghani-Ghorbi
Amir Behnam Kharazmi
author_sort Parisa Delkash
collection DOAJ
description Background: Ventilator-Associated Pneumonia (VAP) is one of the most common nosocomial infections that occurs after intubation in patients with mechanical ventilation. Methods: This cross-sectional descriptive study was conducted in a group of patients admitted to the ICU with a sample size of 120 patients. patients were visited daily at the beginning of admission to the ICU and the study began by considering the entry and exit criteria. To achieve the research objectives, researchers visited the ICI department daily and identified eligible patients. Also, in this study, the demographic profile form of the patients was designed, and their information was completed by the researchers according to the information in the patients' clinical records. The questions of the demographic profile form were completed using an interview with the patient's companion and a study of the patient's hospitalization records. The data from this study were entered into SPSS version 18 and analysed using chi-square, regression, Mann-Whitney and other statistical tests. Results: According to the findings, 120 patients admitted to the ICU were included in the study, of which 48.3% were male and 51.7% were female. The incidence of VAP in 24 patients (20%) was reported. most of the VAP Group patients were male with a rate of 70.8%, age group 70-80 years with a rate of 66.7%, a history of smoking with a rate of 100% and consciousness above 9 with a rate of 70.8%. Also, in patients with VAP, 91.7% of patients with cancer and 41.7% of patients with rheumatoid arthritis had comorbidities, which was significant compared to the No-VAP Group (P value<0.05). Conclusion: Given the high prevalence of VAP and its role in patient mortality, preventive interventions are recommended to reduce the incidence of VAP.
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spelling doaj-art-3a2f7c7b378f4eb0bfd7630304c01c672025-08-20T02:28:42ZengTehran University of Medical SciencesArchives of Anesthesia and Critical Care2423-58492025-02-0111310.18502/aacc.v11i3.18492Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care UnitParisa Delkash0Soheila Sadeghi1Seyed Amir Sheikholeslami2Mahmoud Dehghani-Ghorbi3Amir Behnam Kharazmi4Department of Adult Rheumatology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Internal Medicine, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. & Department of Adult Hematology & Oncology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Adult Hematology & Oncology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Adult Hematology & Oncology, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Internal Medicine, Imam Hossein Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Background: Ventilator-Associated Pneumonia (VAP) is one of the most common nosocomial infections that occurs after intubation in patients with mechanical ventilation. Methods: This cross-sectional descriptive study was conducted in a group of patients admitted to the ICU with a sample size of 120 patients. patients were visited daily at the beginning of admission to the ICU and the study began by considering the entry and exit criteria. To achieve the research objectives, researchers visited the ICI department daily and identified eligible patients. Also, in this study, the demographic profile form of the patients was designed, and their information was completed by the researchers according to the information in the patients' clinical records. The questions of the demographic profile form were completed using an interview with the patient's companion and a study of the patient's hospitalization records. The data from this study were entered into SPSS version 18 and analysed using chi-square, regression, Mann-Whitney and other statistical tests. Results: According to the findings, 120 patients admitted to the ICU were included in the study, of which 48.3% were male and 51.7% were female. The incidence of VAP in 24 patients (20%) was reported. most of the VAP Group patients were male with a rate of 70.8%, age group 70-80 years with a rate of 66.7%, a history of smoking with a rate of 100% and consciousness above 9 with a rate of 70.8%. Also, in patients with VAP, 91.7% of patients with cancer and 41.7% of patients with rheumatoid arthritis had comorbidities, which was significant compared to the No-VAP Group (P value<0.05). Conclusion: Given the high prevalence of VAP and its role in patient mortality, preventive interventions are recommended to reduce the incidence of VAP. https://aacc.tums.ac.ir/index.php/aacc/article/view/1139Ventilator-associated pneumoniaIntensive Care UnitIncidenceRisk factors
spellingShingle Parisa Delkash
Soheila Sadeghi
Seyed Amir Sheikholeslami
Mahmoud Dehghani-Ghorbi
Amir Behnam Kharazmi
Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit
Archives of Anesthesia and Critical Care
Ventilator-associated pneumonia
Intensive Care Unit
Incidence
Risk factors
title Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit
title_full Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit
title_fullStr Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit
title_full_unstemmed Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit
title_short Incidence, Risk Factors, and Outcome of Ventilator-Associated Pneumonia in an Intensive Care Unit
title_sort incidence risk factors and outcome of ventilator associated pneumonia in an intensive care unit
topic Ventilator-associated pneumonia
Intensive Care Unit
Incidence
Risk factors
url https://aacc.tums.ac.ir/index.php/aacc/article/view/1139
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