Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems

Introduction: Surgical wounds that fail to heal or that develop complications such as infection or dehiscence are challenging problem that health care has to deal with everyday. Negative Pressure Wound Therapy (NPWT) has emerged as an important tool for managing complex wounds. This review aims to...

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Main Authors: Piotr Marcjasz, Anna Bioły, Agnieszka Buliszak, Monika Babczyńska, Agnieszka Borończyk, Piotr Zając
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2025-04-01
Series:Quality in Sport
Subjects:
Online Access:https://apcz.umk.pl/QS/article/view/59833
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author Piotr Marcjasz
Anna Bioły
Agnieszka Buliszak
Monika Babczyńska
Agnieszka Borończyk
Piotr Zając
author_facet Piotr Marcjasz
Anna Bioły
Agnieszka Buliszak
Monika Babczyńska
Agnieszka Borończyk
Piotr Zając
author_sort Piotr Marcjasz
collection DOAJ
description Introduction: Surgical wounds that fail to heal or that develop complications such as infection or dehiscence are challenging problem that health care has to deal with everyday. Negative Pressure Wound Therapy (NPWT) has emerged as an important tool for managing complex wounds. This review aims to summarize the mechanisms by which NPWT supports wound healing, estimate the clinical efficacy of NPWT in surgical wounds and compare available NPWT systems. Materials and methods: A literature review was conducted using the databases such as Pubmed and Google Scholar. State of Knowledge: NPWT involves a sealed dressing attached to a suction pump that applies subatmospheric pressure to the wound. There are four major mechanisms that lead straight to the effect: microdeformation [14]; macrodeformation [13], fluid removal [15]; stabilization of wound environment [11]. Clinically, NPWT has demonstrated improved healing rates in chronic wounds (e.g., diabetic foot ulcers) [5, 6] and decreased surgical site infection and seroma in high-risk surgical incisions [7, 8]. Conclusions: NPWT upgrades healing by stabilizing environment of wound, enhancing granulation and closing wound faster. Evidence confirms its efficacy in reducing wound complications in both open and closed surgical wounds. NPWT has become an invaluable tool in surgical wound management, however it is still important to use it in selected group of patients.
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spelling doaj-art-3a233ac712a14dd38407e50d1cfe090b2025-08-20T02:18:35ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-04-014010.12775/QS.2025.40.59833Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT SystemsPiotr Marcjasz0https://orcid.org/0009-0007-8247-5200Anna Bioły1https://orcid.org/0009-0005-2246-3537Agnieszka Buliszak2https://orcid.org/0009-0002-2434-4775Monika Babczyńska3https://orcid.org/0009-0007-8430-5838Agnieszka Borończyk4https://orcid.org/0009-0001-3866-9370Piotr Zając5https://orcid.org/0009-0004-1516-8487Medical University of Silesia, Ul. Poniatowskiego 15, 40-055 Katowice, Poland Medical University of Silesia, Ul. Poniatowskiego 15, 40-055 Katowice, Poland Medical University of Silesia, Ul. Poniatowskiego 15, 40-055 Katowice, PolandMedical University of Silesia, Ul. Poniatowskiego 15, 40-055 Katowice, PolandMedical University of Silesia, Ul. Poniatowskiego 15, 40-055 Katowice, PolandUpper Silesian Medical Center of Prof. Leszek Giec of the Silesian Medical University, 
Ziołowa 45-47, 40-635 Katowice – Ochojec Introduction: Surgical wounds that fail to heal or that develop complications such as infection or dehiscence are challenging problem that health care has to deal with everyday. Negative Pressure Wound Therapy (NPWT) has emerged as an important tool for managing complex wounds. This review aims to summarize the mechanisms by which NPWT supports wound healing, estimate the clinical efficacy of NPWT in surgical wounds and compare available NPWT systems. Materials and methods: A literature review was conducted using the databases such as Pubmed and Google Scholar. State of Knowledge: NPWT involves a sealed dressing attached to a suction pump that applies subatmospheric pressure to the wound. There are four major mechanisms that lead straight to the effect: microdeformation [14]; macrodeformation [13], fluid removal [15]; stabilization of wound environment [11]. Clinically, NPWT has demonstrated improved healing rates in chronic wounds (e.g., diabetic foot ulcers) [5, 6] and decreased surgical site infection and seroma in high-risk surgical incisions [7, 8]. Conclusions: NPWT upgrades healing by stabilizing environment of wound, enhancing granulation and closing wound faster. Evidence confirms its efficacy in reducing wound complications in both open and closed surgical wounds. NPWT has become an invaluable tool in surgical wound management, however it is still important to use it in selected group of patients. https://apcz.umk.pl/QS/article/view/59833Negative Pressure Wound Therapy (NPWT)Vacuum-assisted closure (VAC)wounds healingsurgical wounds
spellingShingle Piotr Marcjasz
Anna Bioły
Agnieszka Buliszak
Monika Babczyńska
Agnieszka Borończyk
Piotr Zając
Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems
Quality in Sport
Negative Pressure Wound Therapy (NPWT)
Vacuum-assisted closure (VAC)
wounds healing
surgical wounds
title Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems
title_full Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems
title_fullStr Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems
title_full_unstemmed Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems
title_short Negative Pressure Wound Therapy in Surgical Wound Management: 
Mechanisms, Clinical Outcomes, and Comparative Analysis of Modern NPWT Systems
title_sort negative pressure wound therapy in surgical wound management 
mechanisms clinical outcomes and comparative analysis of modern npwt systems
topic Negative Pressure Wound Therapy (NPWT)
Vacuum-assisted closure (VAC)
wounds healing
surgical wounds
url https://apcz.umk.pl/QS/article/view/59833
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