Berberine in the treatment of radiation-induced skin injury: insights from proteomics and network pharmacology

Berberine in the treatment of radiation-induced skin injury: insights from proteomics and network pharmacology

BackgroundRadiation-induced skin injury (RISI) is a notable complication of cancer radiotherapy, impacting patients’ quality of life. Existing interventions mainly address symptoms, with limited success in targeting the fundamental mechanisms. Berberine (BBR), a bioactive compound recognized for its...

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Main Authors:	Jie Zou, Xia-Juan Xiao, Ping Zhang, Xing-Zi Huang, Jing Wang, Chun-Qin Tao, Xiao-Lan Ou, Gong Chen, Ting-Hao He, Long Yang, Biao Huang, Dao-Jiang Yu, Yu Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Pharmacology
Subjects:	berberine radiation-induced skin injury (RISI) proteomics network pharmacology wound healing
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1542851/full
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