Efficient Management of Multiple Domains in Psoriatic Arthritis: Target Treatment Goals and Streamlined Clinical Assessment in a Short Session
Psoriatic arthritis (PsA) is a chronic, immune-mediated, inflammatory arthropathy that presents with inflammation of the joints and entheses, including those of the axial skeleton, and is associated with increased mortality from cardiovascular diseases. Diagnosis is primarily based on clinical pheno...
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| Format: | Article |
| Language: | English |
| Published: |
World Scientific Publishing
2024-01-01
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| Series: | Journal of Clinical Rheumatology and Immunology |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S2661341724740055 |
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| Summary: | Psoriatic arthritis (PsA) is a chronic, immune-mediated, inflammatory arthropathy that presents with inflammation of the joints and entheses, including those of the axial skeleton, and is associated with increased mortality from cardiovascular diseases. Diagnosis is primarily based on clinical phenotype because of the diversity of the associated features, which can include skin and nail disease, dactylitis, uveitis, and arthritis. Early detection and timely management are crucial for improving clinical outcomes and patients’ quality of life. This lecture will focus on the management of the multiple domains in psoriatic arthritis and clinical insights on incorporating insights from clinical trials into daily clinical practice by streamlining clinical assessment in a short session. The lecture will begin by reviewing the epidemiology and pathophysiology of PsA, emphasizing the inflammatory nature of PsA. The clinical domains of PsA including skin psoriasis, arthritis, dactylitis, enthesitis and axial involvement will be discussed, highlighting the importance of targeting multiple PsA domains to improve PsA patient’s physical functions and quality of life. The lecture will then delve into the clinical management of PsA. We will discuss the current recommendations for PsA assessment, including measurement of different clinical domains of PsA. We will explore the PsA assessment in clinical trials and the streamlining strategies of assessment in real-life setting. The management strategies for PsA will then be focused, emphasizing the importance of targeting improvement in multiple clinical disease domains of PsA. We will explore the current evidence-based guidelines for pharmacological treatments, including the role of different biological disease-modifying antirheumatic drugs. Finally, the lecture will end with a real-world case sharing session, highlighting the importance of targeting multiple PsA domain by individualized treatment approaches to improve patient’s health outcomes and quality of life. This lecture aims to equip clinicians by overseas medical expertise on optimizing routine clinical management of multiple disease domains in PsA, ultimately facilitating individualized care to PsA patient to improve their overall clinical outcomes. |
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| ISSN: | 2661-3417 2661-3425 |