Extracellular matrix stiffness regulates colorectal cancer progression via HSF4
Abstract Background Colorectal cancer (CRC) has high incidence and mortality rates, with severe prognoses during invasion and metastasis stages. Despite advancements in diagnostic and therapeutic technologies, the impact of the tumour microenvironment, particularly extracellular matrix (ECM) stiffne...
Saved in:
Main Authors: | Kangtao Wang, Siyi Ning, Shuai Zhang, Mingming Jiang, Yan Huang, Haiping Pei, Ming Li, Fengbo Tan |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
|
Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-025-03297-8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer
by: Ximo Zhang, et al.
Published: (2025-01-01) -
Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer
by: Stefan A. Cieslik, et al.
Published: (2025-01-01) -
Comprehensive single-cell atlas of colorectal neuroendocrine tumors with liver metastases: unraveling tumor microenvironment heterogeneity between primary lesions and metastases
by: Yiqiao Deng, et al.
Published: (2025-01-01) -
Metformin in the treatment of colorectal cancer and neuroendocrine tumours
by: Karolina Daniłowska, et al.
Published: (2024-08-01) -
Markers of metastatic colorectal cancer
by: Piotr Myśliwiec, et al.
Published: (2019-05-01)