Clinical Outcome of Hypertensive Uveitis

Purpose. To review the clinical outcome of patients with hypertensive uveitis. Methods. Retrospective review of uveitis patients with elevated intraocular pressure (IOP) > 25 mmHg and >1-year follow-up. Data are uveitis type, etiology, viral (VU) and nonviral uveitis (NVU), IOP, and medical an...

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Main Authors: Deborah Lewkowicz, François Willermain, Lia Judice Relvas, Dorine Makhoul, Sarah Janssens, Xavier Janssens, Laure Caspers
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/974870
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author Deborah Lewkowicz
François Willermain
Lia Judice Relvas
Dorine Makhoul
Sarah Janssens
Xavier Janssens
Laure Caspers
author_facet Deborah Lewkowicz
François Willermain
Lia Judice Relvas
Dorine Makhoul
Sarah Janssens
Xavier Janssens
Laure Caspers
author_sort Deborah Lewkowicz
collection DOAJ
description Purpose. To review the clinical outcome of patients with hypertensive uveitis. Methods. Retrospective review of uveitis patients with elevated intraocular pressure (IOP) > 25 mmHg and >1-year follow-up. Data are uveitis type, etiology, viral (VU) and nonviral uveitis (NVU), IOP, and medical and/or surgical treatment. Results. In 61 patients, IOP values are first 32.9 mmHg (SD: 9.0), highest 36.6 mmHg (SD: 9.9), 3 months after the first episode 19.54 mmHg (SD: 9.16), and end of follow-up 15.5 mmHg (SD: 6.24). Patients with VU (n=25) were older (50.6 y/35.7 y, p=0.014) and had more unilateral disease (100%/72.22%  p=0.004) than those with NVU (n=36). Thirty patients (49.2%) had an elevated IOP before topical corticosteroid treatment. Patients with viral uveitis might have higher first elevated IOP (36.0/27.5 mmHg, p=0,008) and maximal IOP (40.28/34.06 mmHg, p=0.0148) but this was not significant when limited to the measurements before the use of topical corticosteroids (p=0.260 and 0.160). Glaucoma occurred in 15 patients (24.59%) and was suspected in 11 (18.03%) without difference in viral and nonviral groups (p=0.774). Conclusion. Patients with VU were older and had more unilateral hypertensive uveitis. Glaucoma frequently complicates hypertensive uveitis. Half of the patients had an elevated IOP before topical corticosteroid treatment.
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spelling doaj-art-3a148ebcdb08459ba93f17821a1c6d6c2025-02-03T05:53:05ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/974870974870Clinical Outcome of Hypertensive UveitisDeborah Lewkowicz0François Willermain1Lia Judice Relvas2Dorine Makhoul3Sarah Janssens4Xavier Janssens5Laure Caspers6CHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumCHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumCHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumCHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumCHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumCHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumCHU Saint-Pierre, Université Libre de Bruxelles (ULB), 1000 Brussels, BelgiumPurpose. To review the clinical outcome of patients with hypertensive uveitis. Methods. Retrospective review of uveitis patients with elevated intraocular pressure (IOP) > 25 mmHg and >1-year follow-up. Data are uveitis type, etiology, viral (VU) and nonviral uveitis (NVU), IOP, and medical and/or surgical treatment. Results. In 61 patients, IOP values are first 32.9 mmHg (SD: 9.0), highest 36.6 mmHg (SD: 9.9), 3 months after the first episode 19.54 mmHg (SD: 9.16), and end of follow-up 15.5 mmHg (SD: 6.24). Patients with VU (n=25) were older (50.6 y/35.7 y, p=0.014) and had more unilateral disease (100%/72.22%  p=0.004) than those with NVU (n=36). Thirty patients (49.2%) had an elevated IOP before topical corticosteroid treatment. Patients with viral uveitis might have higher first elevated IOP (36.0/27.5 mmHg, p=0,008) and maximal IOP (40.28/34.06 mmHg, p=0.0148) but this was not significant when limited to the measurements before the use of topical corticosteroids (p=0.260 and 0.160). Glaucoma occurred in 15 patients (24.59%) and was suspected in 11 (18.03%) without difference in viral and nonviral groups (p=0.774). Conclusion. Patients with VU were older and had more unilateral hypertensive uveitis. Glaucoma frequently complicates hypertensive uveitis. Half of the patients had an elevated IOP before topical corticosteroid treatment.http://dx.doi.org/10.1155/2015/974870
spellingShingle Deborah Lewkowicz
François Willermain
Lia Judice Relvas
Dorine Makhoul
Sarah Janssens
Xavier Janssens
Laure Caspers
Clinical Outcome of Hypertensive Uveitis
Journal of Ophthalmology
title Clinical Outcome of Hypertensive Uveitis
title_full Clinical Outcome of Hypertensive Uveitis
title_fullStr Clinical Outcome of Hypertensive Uveitis
title_full_unstemmed Clinical Outcome of Hypertensive Uveitis
title_short Clinical Outcome of Hypertensive Uveitis
title_sort clinical outcome of hypertensive uveitis
url http://dx.doi.org/10.1155/2015/974870
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