Fecal carriage of multidrug-resistant organisms increases the risk of hepatic encephalopathy in patients with cirrhosis: insights from gut microbiota and metabolite features

Fecal carriage of multidrug-resistant organisms increases the risk of hepatic encephalopathy in patients with cirrhosis: insights from gut microbiota and metabolite features

Abstract Background The impact of the fecal multidrug-resistant organism (MDRO) carriage on the gut microbiota, metabolite alterations, and cirrhosis-related complications remains unclear. Methods Eighty-eight patients with cirrhosis and 22 healthy volunteers were analyzed for plasma metabolites, fe...

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Main Authors: Pei-Shan Wu, Pei-Chang Lee, Tien-En Chang, Yun-Cheng Hsieh, Chi-Wei Huang, Chao-Hsiung Lin, Yi-Long Huang, Yi-Tsung Lin, Teh-Ia Huo, Bernd Schnabl, Kuei-Chuan Lee, Ming-Chih Hou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Gut Pathogens
Subjects:
Multidrug resistant organisms
Cirrhosis-associated complications
Microbiota
Metabolite
Hepatic encephalopathy
Online Access:https://doi.org/10.1186/s13099-025-00706-3
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