Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids
Objective To investigate the changes in liver and kidney function, red blood cell (RBC) count and hemoglobin (HGB) levels in patients undergoing ultrasound-guided percutaneous microwave ablation (UPMWA) for uterine fibroids on postoperative day 1.Methods The changes in liver and kidney function, RBC...
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2024.2338542 |
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| author | Xiao-Yu Huang Qin-Sheng Lu Shao-Ping Wu Han-Ming Huang Yong-Fa Zhang |
| author_facet | Xiao-Yu Huang Qin-Sheng Lu Shao-Ping Wu Han-Ming Huang Yong-Fa Zhang |
| author_sort | Xiao-Yu Huang |
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| description | Objective To investigate the changes in liver and kidney function, red blood cell (RBC) count and hemoglobin (HGB) levels in patients undergoing ultrasound-guided percutaneous microwave ablation (UPMWA) for uterine fibroids on postoperative day 1.Methods The changes in liver and kidney function, RBC count and HGB levels in 181 patients who underwent selective UPMWA in the Second Affiliated Hospital of Shantou University Medical College, China, between August 2017 and January 2023 were retrospectively analyzed.Results All patients underwent UPMWA for uterine fibroids; 179 patients had multiple uterine fibroids and 2 patients had single uterine fibroids. The maximum fibroid diameter ranged from 18 to 140 mm, with an average of 68.3 mm. Ultrasound imaging was used to confirm that the blood flow signal within the mass had disappeared in all patients, indicating that the ablation was effective. Within 24 h, compared with before UPMWA, levels of total bilirubin, direct bilirubin, indirect bilirubin and aspartate aminotransferase had significantly increased (p < 0.01), whereas levels of total protein, albumin, globulin, alanine aminotransferase, creatinine and urea had significantly decreased (p < 0.01). Acute kidney injury (AKI) occurred in 1 of the 181 patients. The RBC count and HGB levels decreased significantly after UPMWA (p < 0.01).Conclusion Ultrasound-guided percutaneous microwave ablation for uterine fibroids can impose a higher detoxification load on the liver and cause thermal damage to and the destruction of RBCs within local circulation, potentially leading to AKI. Protein levels significantly decreased after UPMWA. Therefore, perioperative organ function protection measures and treatment should be actively integrated into clinical practice to improve prognosis and enhance recovery. |
| format | Article |
| id | doaj-art-3a0ca16959da4f96b9e070d4d3bd4d2d |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-3a0ca16959da4f96b9e070d4d3bd4d2d2025-01-03T09:30:27ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2024.2338542Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroidsXiao-Yu Huang0Qin-Sheng Lu1Shao-Ping Wu2Han-Ming Huang3Yong-Fa Zhang4Department of Anesthesiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, ChinaDepartment of Anesthesiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, ChinaObjective To investigate the changes in liver and kidney function, red blood cell (RBC) count and hemoglobin (HGB) levels in patients undergoing ultrasound-guided percutaneous microwave ablation (UPMWA) for uterine fibroids on postoperative day 1.Methods The changes in liver and kidney function, RBC count and HGB levels in 181 patients who underwent selective UPMWA in the Second Affiliated Hospital of Shantou University Medical College, China, between August 2017 and January 2023 were retrospectively analyzed.Results All patients underwent UPMWA for uterine fibroids; 179 patients had multiple uterine fibroids and 2 patients had single uterine fibroids. The maximum fibroid diameter ranged from 18 to 140 mm, with an average of 68.3 mm. Ultrasound imaging was used to confirm that the blood flow signal within the mass had disappeared in all patients, indicating that the ablation was effective. Within 24 h, compared with before UPMWA, levels of total bilirubin, direct bilirubin, indirect bilirubin and aspartate aminotransferase had significantly increased (p < 0.01), whereas levels of total protein, albumin, globulin, alanine aminotransferase, creatinine and urea had significantly decreased (p < 0.01). Acute kidney injury (AKI) occurred in 1 of the 181 patients. The RBC count and HGB levels decreased significantly after UPMWA (p < 0.01).Conclusion Ultrasound-guided percutaneous microwave ablation for uterine fibroids can impose a higher detoxification load on the liver and cause thermal damage to and the destruction of RBCs within local circulation, potentially leading to AKI. Protein levels significantly decreased after UPMWA. Therefore, perioperative organ function protection measures and treatment should be actively integrated into clinical practice to improve prognosis and enhance recovery.https://www.tandfonline.com/doi/10.1080/02656736.2024.2338542Uterine fibroidsultrasound-guided percutaneous microwave ablationacute kidney injuryliver and kidney functionperioperative organ protection |
| spellingShingle | Xiao-Yu Huang Qin-Sheng Lu Shao-Ping Wu Han-Ming Huang Yong-Fa Zhang Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids International Journal of Hyperthermia Uterine fibroids ultrasound-guided percutaneous microwave ablation acute kidney injury liver and kidney function perioperative organ protection |
| title | Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids |
| title_full | Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids |
| title_fullStr | Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids |
| title_full_unstemmed | Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids |
| title_short | Changes in liver and kidney function, red blood cell count and hemoglobin levels 1 day after ultrasound-guided percutaneous microwave ablation for uterine fibroids |
| title_sort | changes in liver and kidney function red blood cell count and hemoglobin levels 1 day after ultrasound guided percutaneous microwave ablation for uterine fibroids |
| topic | Uterine fibroids ultrasound-guided percutaneous microwave ablation acute kidney injury liver and kidney function perioperative organ protection |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2024.2338542 |
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