Cell Signals Influencing Hepatic Fibrosis
Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2012/158547 |
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| _version_ | 1832545496892178432 |
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| author | Min Cong Keiko Iwaisako Chunyan Jiang Tatiana Kisseleva |
| author_facet | Min Cong Keiko Iwaisako Chunyan Jiang Tatiana Kisseleva |
| author_sort | Min Cong |
| collection | DOAJ |
| description | Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets. |
| format | Article |
| id | doaj-art-3a0302dda3af4df0883c9875ac872b3a |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-3a0302dda3af4df0883c9875ac872b3a2025-02-03T07:25:36ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/158547158547Cell Signals Influencing Hepatic FibrosisMin Cong0Keiko Iwaisako1Chunyan Jiang2Tatiana Kisseleva3Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USADepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USADepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USADepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USALiver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.http://dx.doi.org/10.1155/2012/158547 |
| spellingShingle | Min Cong Keiko Iwaisako Chunyan Jiang Tatiana Kisseleva Cell Signals Influencing Hepatic Fibrosis International Journal of Hepatology |
| title | Cell Signals Influencing Hepatic Fibrosis |
| title_full | Cell Signals Influencing Hepatic Fibrosis |
| title_fullStr | Cell Signals Influencing Hepatic Fibrosis |
| title_full_unstemmed | Cell Signals Influencing Hepatic Fibrosis |
| title_short | Cell Signals Influencing Hepatic Fibrosis |
| title_sort | cell signals influencing hepatic fibrosis |
| url | http://dx.doi.org/10.1155/2012/158547 |
| work_keys_str_mv | AT mincong cellsignalsinfluencinghepaticfibrosis AT keikoiwaisako cellsignalsinfluencinghepaticfibrosis AT chunyanjiang cellsignalsinfluencinghepaticfibrosis AT tatianakisseleva cellsignalsinfluencinghepaticfibrosis |