A hepatitis B virus (HBV) sequence variation graph improves alignment and sample-specific consensus sequence construction.

A hepatitis B virus (HBV) sequence variation graph improves alignment and sample-specific consensus sequence construction.

Nearly 300 million individuals live with chronic hepatitis B virus (HBV) infection (CHB), for which no curative therapy is available. As viral diversity is associated with pathogenesis and immunological control of infection, improved methods to characterize this diversity could aid drug development...

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Main Authors: Dylan Duchen, Steven J Clipman, Candelaria Vergara, Chloe L Thio, David L Thomas, Priya Duggal, Genevieve L Wojcik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301069&type=printable
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