Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment
Abstract Background To investigate the anatomical and functional outcomes of macular hole-associated retinal detachment (MHRD) after vitrectomy using the inverted internal limiting membrane (ILM) flap technique with autologous blood clot (ABC). Methods This retrospective observational study included...
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BMC
2025-01-01
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| Series: | Eye and Vision |
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| Online Access: | https://doi.org/10.1186/s40662-024-00417-x |
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| author | Ke Zhu Yingchao Wang Boya Lei Ling Chen Yanqiong Zhang Qing Chang Gezhi Xu Yingqin Ni |
| author_facet | Ke Zhu Yingchao Wang Boya Lei Ling Chen Yanqiong Zhang Qing Chang Gezhi Xu Yingqin Ni |
| author_sort | Ke Zhu |
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| description | Abstract Background To investigate the anatomical and functional outcomes of macular hole-associated retinal detachment (MHRD) after vitrectomy using the inverted internal limiting membrane (ILM) flap technique with autologous blood clot (ABC). Methods This retrospective observational study included 80 eyes with MHRD that underwent vitrectomy with ILM flap without (46 eyes) or with ABC (34 eyes). Fundus photography and optical coherence tomography were evaluated. The pre- and postoperative best-corrected visual acuities (BCVAs) and BCVA improvement were compared between the two groups. Results The MH closure rates after initial surgery were similar in the ILM flap group and ILM flap with ABC group [40 (87%) vs. 29 (85%) eyes, respectively]. The proportion of eyes with hyperreflective bridging tissue (HBT) was lower in the ILM flap group than ILM flap with ABC group [13 (32%) vs. 16 (55%) eyes, P = 0.060]. The postoperative improvement in BCVA was significantly better in the ILM flap group (P = 0.027). Multiple linear regression analysis revealed that preoperative BCVA was positively associated with postoperative improvement in BCVA (β = 0.638, P = 0.000), while the ILM flap with ABC technique was negatively associated with postoperative improvement in BCVA (β = − 0.299, P = 0.039, adjusted r2 = 0.415). Conclusions The inverted ILM flap technique alone resulted in better foveal configurations and visual outcomes than the ILM flap technique combined with ABC in patients with MHRD. |
| format | Article |
| id | doaj-art-39f9b05532e14a398d76fc5c2b930140 |
| institution | Kabale University |
| issn | 2326-0254 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | Eye and Vision |
| spelling | doaj-art-39f9b05532e14a398d76fc5c2b9301402025-01-05T12:08:55ZengBMCEye and Vision2326-02542025-01-0112111010.1186/s40662-024-00417-xComparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachmentKe Zhu0Yingchao Wang1Boya Lei2Ling Chen3Yanqiong Zhang4Qing Chang5Gezhi Xu6Yingqin Ni7Eye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityEye Institute and Department of Ophthalmology, Eye and Ear Nose, Throat Hospital of Fudan UniversityAbstract Background To investigate the anatomical and functional outcomes of macular hole-associated retinal detachment (MHRD) after vitrectomy using the inverted internal limiting membrane (ILM) flap technique with autologous blood clot (ABC). Methods This retrospective observational study included 80 eyes with MHRD that underwent vitrectomy with ILM flap without (46 eyes) or with ABC (34 eyes). Fundus photography and optical coherence tomography were evaluated. The pre- and postoperative best-corrected visual acuities (BCVAs) and BCVA improvement were compared between the two groups. Results The MH closure rates after initial surgery were similar in the ILM flap group and ILM flap with ABC group [40 (87%) vs. 29 (85%) eyes, respectively]. The proportion of eyes with hyperreflective bridging tissue (HBT) was lower in the ILM flap group than ILM flap with ABC group [13 (32%) vs. 16 (55%) eyes, P = 0.060]. The postoperative improvement in BCVA was significantly better in the ILM flap group (P = 0.027). Multiple linear regression analysis revealed that preoperative BCVA was positively associated with postoperative improvement in BCVA (β = 0.638, P = 0.000), while the ILM flap with ABC technique was negatively associated with postoperative improvement in BCVA (β = − 0.299, P = 0.039, adjusted r2 = 0.415). Conclusions The inverted ILM flap technique alone resulted in better foveal configurations and visual outcomes than the ILM flap technique combined with ABC in patients with MHRD.https://doi.org/10.1186/s40662-024-00417-xMacular hole-associated retinal detachmentInternal limiting membrane flap techniqueAutologous blood clotMacular hole closureBest-corrected visual acuity |
| spellingShingle | Ke Zhu Yingchao Wang Boya Lei Ling Chen Yanqiong Zhang Qing Chang Gezhi Xu Yingqin Ni Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment Eye and Vision Macular hole-associated retinal detachment Internal limiting membrane flap technique Autologous blood clot Macular hole closure Best-corrected visual acuity |
| title | Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment |
| title_full | Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment |
| title_fullStr | Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment |
| title_full_unstemmed | Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment |
| title_short | Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment |
| title_sort | comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole associated retinal detachment |
| topic | Macular hole-associated retinal detachment Internal limiting membrane flap technique Autologous blood clot Macular hole closure Best-corrected visual acuity |
| url | https://doi.org/10.1186/s40662-024-00417-x |
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