Integrative analysis reveals key molecular mechanisms and prognostic model for Ethylnitrosourea-induced gliomagenesis

Integrative analysis reveals key molecular mechanisms and prognostic model for Ethylnitrosourea-induced gliomagenesis

Abstract Background Ethylnitrosourea (ENU) is a potent mutagen that induces gliomas in experimental models. Understanding the molecular mechanisms underlying ENU-induced gliomagenesis can provide insights into glioma pathogenesis and potential therapeutic targets. Methods We analyzed gene expression...

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Bibliographic Details
Main Authors: Bo Tan, Tao Chen, Peng Song, Feng Lin, Shuangyin He, Shiyuan Zhang, Xiaohong Yin
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Gliomagenesis
N-ethyl-N-nitrosourea
Immune cell infiltration
Bioinformatics
Molecular docking
Prognostic model
Online Access:https://doi.org/10.1186/s40360-025-00919-x
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