Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells

Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells

IntroductionWe investigated the impact of rheumatoid arthritis (RA) associated cytokines and standard of care (SOC) RA therapeutics on immune checkpoint receptor (IR) expression on T cells to gain insights to disease pathology and therapeutic avenues.MethodsWe assessed IR expression by flow cytometr...

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Bibliographic Details
Main Authors: Dana Emerson, Eve Merriman, Pia P. Yachi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
checkpoint receptor
cytokine
T cell
rheumatoid arthritis
adalimumab
tofacitinib
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1534462/full
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