MicroRNAs and type 2 diabetes
Abstract MicroRNAs (miRNAs) are non-coding single strand RNAs. MiRNAs are encoded by endogenous genes with a length of about 22 nucleotides. MiRNAs play a vital role in the inhibition of post-transcriptional translation of mRNAs. In recent years, studies have discovered that miRNAs play an essensial...
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| Format: | Article |
| Language: | English |
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ELS Publishing (ELSP)
2019-06-01
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| Series: | ExRNA |
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| Online Access: | http://link.springer.com/article/10.1186/s41544-019-0038-5 |
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| _version_ | 1849415302151929856 |
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| author | Jiali Deng Feifan Guo |
| author_facet | Jiali Deng Feifan Guo |
| author_sort | Jiali Deng |
| collection | DOAJ |
| description | Abstract MicroRNAs (miRNAs) are non-coding single strand RNAs. MiRNAs are encoded by endogenous genes with a length of about 22 nucleotides. MiRNAs play a vital role in the inhibition of post-transcriptional translation of mRNAs. In recent years, studies have discovered that miRNAs play an essensial role in the pathogenesis of type 2 diabetes. In addition, the discovery of miRNAs in the serum and plasma also provides a potential target for the discovery of disease markers. Taken together, preliminary data suggest a potential role of miRNAs in type 2 diabetes, however more clinical trials need to be studied. |
| format | Article |
| id | doaj-art-39ef5e707a154ea7869ab3bc6f36e242 |
| institution | Kabale University |
| issn | 2398-0060 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | ELS Publishing (ELSP) |
| record_format | Article |
| series | ExRNA |
| spelling | doaj-art-39ef5e707a154ea7869ab3bc6f36e2422025-08-20T03:33:35ZengELS Publishing (ELSP)ExRNA2398-00602019-06-01111510.1186/s41544-019-0038-5MicroRNAs and type 2 diabetesJiali Deng0Feifan Guo1CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of SciencesCAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of SciencesAbstract MicroRNAs (miRNAs) are non-coding single strand RNAs. MiRNAs are encoded by endogenous genes with a length of about 22 nucleotides. MiRNAs play a vital role in the inhibition of post-transcriptional translation of mRNAs. In recent years, studies have discovered that miRNAs play an essensial role in the pathogenesis of type 2 diabetes. In addition, the discovery of miRNAs in the serum and plasma also provides a potential target for the discovery of disease markers. Taken together, preliminary data suggest a potential role of miRNAs in type 2 diabetes, however more clinical trials need to be studied.http://link.springer.com/article/10.1186/s41544-019-0038-5microRNAsInsulin resistanceDiabetes |
| spellingShingle | Jiali Deng Feifan Guo MicroRNAs and type 2 diabetes ExRNA microRNAs Insulin resistance Diabetes |
| title | MicroRNAs and type 2 diabetes |
| title_full | MicroRNAs and type 2 diabetes |
| title_fullStr | MicroRNAs and type 2 diabetes |
| title_full_unstemmed | MicroRNAs and type 2 diabetes |
| title_short | MicroRNAs and type 2 diabetes |
| title_sort | micrornas and type 2 diabetes |
| topic | microRNAs Insulin resistance Diabetes |
| url | http://link.springer.com/article/10.1186/s41544-019-0038-5 |
| work_keys_str_mv | AT jialideng micrornasandtype2diabetes AT feifanguo micrornasandtype2diabetes |