MicroRNAs and type 2 diabetes
Abstract MicroRNAs (miRNAs) are non-coding single strand RNAs. MiRNAs are encoded by endogenous genes with a length of about 22 nucleotides. MiRNAs play a vital role in the inhibition of post-transcriptional translation of mRNAs. In recent years, studies have discovered that miRNAs play an essensial...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
ELS Publishing (ELSP)
2019-06-01
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| Series: | ExRNA |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41544-019-0038-5 |
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| Summary: | Abstract MicroRNAs (miRNAs) are non-coding single strand RNAs. MiRNAs are encoded by endogenous genes with a length of about 22 nucleotides. MiRNAs play a vital role in the inhibition of post-transcriptional translation of mRNAs. In recent years, studies have discovered that miRNAs play an essensial role in the pathogenesis of type 2 diabetes. In addition, the discovery of miRNAs in the serum and plasma also provides a potential target for the discovery of disease markers. Taken together, preliminary data suggest a potential role of miRNAs in type 2 diabetes, however more clinical trials need to be studied. |
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| ISSN: | 2398-0060 |