Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient
Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with s...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2020/8841607 |
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| _version_ | 1850157349908512768 |
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| author | Pratik A. Patel Elizabeth P. Weinzierl Daniel S. Wechsler |
| author_facet | Pratik A. Patel Elizabeth P. Weinzierl Daniel S. Wechsler |
| author_sort | Pratik A. Patel |
| collection | DOAJ |
| description | Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with sickle cell disease, parvovirus infection can cause transient aplastic crisis which can be life-threatening. However, leukocytosis and thrombocytosis are rarely seen. We report leukoerythroblastosis as an unusual presentation of acute parvovirus B19 infection in a previously splenectomized 12-year-old boy with sickle cell disease. |
| format | Article |
| id | doaj-art-39ed2db28ebe46419fe494bb90cfacba |
| institution | OA Journals |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-39ed2db28ebe46419fe494bb90cfacba2025-08-20T02:24:13ZengWileyCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/88416078841607Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell PatientPratik A. Patel0Elizabeth P. Weinzierl1Daniel S. Wechsler2Aflac Cancer & Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, GA, USADepartment of Pathology, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USAAflac Cancer & Blood Disorders Center, Children’s Healthcare of Atlanta, Atlanta, GA, USAParvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with sickle cell disease, parvovirus infection can cause transient aplastic crisis which can be life-threatening. However, leukocytosis and thrombocytosis are rarely seen. We report leukoerythroblastosis as an unusual presentation of acute parvovirus B19 infection in a previously splenectomized 12-year-old boy with sickle cell disease.http://dx.doi.org/10.1155/2020/8841607 |
| spellingShingle | Pratik A. Patel Elizabeth P. Weinzierl Daniel S. Wechsler Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient Case Reports in Pediatrics |
| title | Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient |
| title_full | Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient |
| title_fullStr | Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient |
| title_full_unstemmed | Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient |
| title_short | Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient |
| title_sort | leukoerythroblastosis as an unusual presentation of parvovirus b19 infection in a sickle cell patient |
| url | http://dx.doi.org/10.1155/2020/8841607 |
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