Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges

Abdominal organ segmentation in CT images is crucial for accurate diagnosis, treatment planning, and condition monitoring. However, the annotation process is often hindered by challenges such as low contrast, artifacts, and complex organ structures. While unsupervised domain adaptation (UDA) has sho...

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Main Authors: Xiyu Zhang, Xu Chen, Yang Wang, Dongliang Liu, Yifeng Hong
Format: Article
Language:English
Published: MDPI AG 2025-05-01
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Online Access:https://www.mdpi.com/2078-2489/16/6/460
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author Xiyu Zhang
Xu Chen
Yang Wang
Dongliang Liu
Yifeng Hong
author_facet Xiyu Zhang
Xu Chen
Yang Wang
Dongliang Liu
Yifeng Hong
author_sort Xiyu Zhang
collection DOAJ
description Abdominal organ segmentation in CT images is crucial for accurate diagnosis, treatment planning, and condition monitoring. However, the annotation process is often hindered by challenges such as low contrast, artifacts, and complex organ structures. While unsupervised domain adaptation (UDA) has shown promise in addressing these issues by transferring knowledge from a different modality (source domain), its reliance on both source and target data during training presents a practical challenge in many clinical settings due to data privacy concerns. This study aims to develop a cross-modality abdominal multi-organ segmentation model for label-free CT (target domain) data, leveraging knowledge solely from a pre-trained source domain (MRI) model without accessing the source data. To achieve this, we generate source-like images from target-domain images using a one-way image translation approach with the pre-trained model. These synthesized images preserve the anatomical structure of the target, enabling segmentation predictions from the pre-trained model. To further enhance segmentation accuracy, particularly for organ boundaries and small contours, we introduce an auxiliary translation module with an image decoder and multi-level discriminator. The results demonstrate significant improvements across several performance metrics, including the Dice similarity coefficient (DSC) and average symmetric surface distance (ASSD), highlighting the effectiveness of the proposed method.
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spelling doaj-art-39ec2c0b9827416cbd3fb0b9c95e89682025-08-20T02:21:07ZengMDPI AGInformation2078-24892025-05-0116646010.3390/info16060460Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation ChallengesXiyu Zhang0Xu Chen1Yang Wang2Dongliang Liu3Yifeng Hong4College of Computer Science and Technology, Huaqiao University, Xiamen 361021, ChinaCollege of Computer Science and Technology, Huaqiao University, Xiamen 361021, ChinaCollege of Computer Science and Technology, Huaqiao University, Xiamen 361021, ChinaCollege of Computer Science and Technology, Huaqiao University, Xiamen 361021, ChinaCollege of Computer Science and Technology, Huaqiao University, Xiamen 361021, ChinaAbdominal organ segmentation in CT images is crucial for accurate diagnosis, treatment planning, and condition monitoring. However, the annotation process is often hindered by challenges such as low contrast, artifacts, and complex organ structures. While unsupervised domain adaptation (UDA) has shown promise in addressing these issues by transferring knowledge from a different modality (source domain), its reliance on both source and target data during training presents a practical challenge in many clinical settings due to data privacy concerns. This study aims to develop a cross-modality abdominal multi-organ segmentation model for label-free CT (target domain) data, leveraging knowledge solely from a pre-trained source domain (MRI) model without accessing the source data. To achieve this, we generate source-like images from target-domain images using a one-way image translation approach with the pre-trained model. These synthesized images preserve the anatomical structure of the target, enabling segmentation predictions from the pre-trained model. To further enhance segmentation accuracy, particularly for organ boundaries and small contours, we introduce an auxiliary translation module with an image decoder and multi-level discriminator. The results demonstrate significant improvements across several performance metrics, including the Dice similarity coefficient (DSC) and average symmetric surface distance (ASSD), highlighting the effectiveness of the proposed method.https://www.mdpi.com/2078-2489/16/6/460source-free domain adaptationcontrastive learningmedical image segmentation
spellingShingle Xiyu Zhang
Xu Chen
Yang Wang
Dongliang Liu
Yifeng Hong
Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges
Information
source-free domain adaptation
contrastive learning
medical image segmentation
title Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges
title_full Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges
title_fullStr Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges
title_full_unstemmed Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges
title_short Source-Free Domain Adaptation for Cross-Modality Abdominal Multi-Organ Segmentation Challenges
title_sort source free domain adaptation for cross modality abdominal multi organ segmentation challenges
topic source-free domain adaptation
contrastive learning
medical image segmentation
url https://www.mdpi.com/2078-2489/16/6/460
work_keys_str_mv AT xiyuzhang sourcefreedomainadaptationforcrossmodalityabdominalmultiorgansegmentationchallenges
AT xuchen sourcefreedomainadaptationforcrossmodalityabdominalmultiorgansegmentationchallenges
AT yangwang sourcefreedomainadaptationforcrossmodalityabdominalmultiorgansegmentationchallenges
AT dongliangliu sourcefreedomainadaptationforcrossmodalityabdominalmultiorgansegmentationchallenges
AT yifenghong sourcefreedomainadaptationforcrossmodalityabdominalmultiorgansegmentationchallenges