Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification

Cardiovascular risk (CVR) stratification plays an important role in the primary prevention of atherosclerosis and associated disorders. The standard scales for CVR assessment (Framingham scale, SCORE scale, etc.) are focused on a limited number of traditional risk factors (RFs) and, therefore, neith...

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Main Authors: N. O. Katamadze, L. L. Berstein, Yu. N. Grishkin
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2012-04-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1778
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author N. O. Katamadze
L. L. Berstein
Yu. N. Grishkin
author_facet N. O. Katamadze
L. L. Berstein
Yu. N. Grishkin
author_sort N. O. Katamadze
collection DOAJ
description Cardiovascular risk (CVR) stratification plays an important role in the primary prevention of atherosclerosis and associated disorders. The standard scales for CVR assessment (Framingham scale, SCORE scale, etc.) are focused on a limited number of traditional risk factors (RFs) and, therefore, neither produce precise individual risk estimates, nor increase the effectiveness of preventive interventions. One of the methods for CVR assessment optimisation is the diagnostics of subclinical atherosclerosis, based on the direct visualisation of preclinical atherosclerotic changes in arterial wall. Extracranial carotid artery (CA) ultrasound and assessment of the intima-media thickness (IMT) index or atherosclerotic plaque volume (PV) is an important method of the preclinical atherosclerosis diagnostics. The review discusses pathogenetic mechanisms of IMT increase, the standards of ultrasound IMT assessment and its interpretation, and the role of the information obtained for optimization of the CVR evaluation.
format Article
id doaj-art-39e71bb4154e445bbefd4781b3050473
institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 2012-04-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-39e71bb4154e445bbefd4781b30504732025-08-20T03:57:18Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252012-04-01112768410.15829/1728-8800-2012-2-76-841493Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratificationN. O. Katamadze0L. L. Berstein1Yu. N. Grishkin2St. Petersburg Medical Academy of Post-Diploma Education, St. PetersburgSt. Petersburg Medical Academy of Post-Diploma Education, St. PetersburgSt. Petersburg Medical Academy of Post-Diploma Education, St. PetersburgCardiovascular risk (CVR) stratification plays an important role in the primary prevention of atherosclerosis and associated disorders. The standard scales for CVR assessment (Framingham scale, SCORE scale, etc.) are focused on a limited number of traditional risk factors (RFs) and, therefore, neither produce precise individual risk estimates, nor increase the effectiveness of preventive interventions. One of the methods for CVR assessment optimisation is the diagnostics of subclinical atherosclerosis, based on the direct visualisation of preclinical atherosclerotic changes in arterial wall. Extracranial carotid artery (CA) ultrasound and assessment of the intima-media thickness (IMT) index or atherosclerotic plaque volume (PV) is an important method of the preclinical atherosclerosis diagnostics. The review discusses pathogenetic mechanisms of IMT increase, the standards of ultrasound IMT assessment and its interpretation, and the role of the information obtained for optimization of the CVR evaluation.https://cardiovascular.elpub.ru/jour/article/view/1778cardiovascular risk stratificationsubclinical atherosclerosiscarotid arteriesintima-media thicknessatherosclerotic plaque
spellingShingle N. O. Katamadze
L. L. Berstein
Yu. N. Grishkin
Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
Кардиоваскулярная терапия и профилактика
cardiovascular risk stratification
subclinical atherosclerosis
carotid arteries
intima-media thickness
atherosclerotic plaque
title Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
title_full Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
title_fullStr Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
title_full_unstemmed Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
title_short Subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
title_sort subclinical atherosclerosis diagnostics as a component of a modern strategy for cardiovascular risk stratification
topic cardiovascular risk stratification
subclinical atherosclerosis
carotid arteries
intima-media thickness
atherosclerotic plaque
url https://cardiovascular.elpub.ru/jour/article/view/1778
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AT llberstein subclinicalatherosclerosisdiagnosticsasacomponentofamodernstrategyforcardiovascularriskstratification
AT yungrishkin subclinicalatherosclerosisdiagnosticsasacomponentofamodernstrategyforcardiovascularriskstratification