PIK3R1 and G0S2 are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation

PIK3R1 and G0S2 are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation

Genomic imprinting is the parent-of-origin specific monoallelic expression of genes that result from complex epigenetic interactions. It is often achieved by monoallelic 5-methylcytosine, resulting in the formation of differentially methylated regions (DMRs). These show a bias towards oocyte-derived...

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Bibliographic Details
Main Authors: Dagne Daskeviciute, Becky Sainty, Louise Chappell-Maor, Caitlin Bone, Sarah Russell, Isabel Iglesias-Platas, Philippe Arnaud, Ana Monteagudo-Sánchez, Maxim V.C Greenberg, Keran Chen, Africa Manero Azua, Guiomar Perez de Nanclares, Jon Lartey, David Monk
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Epigenetics
Subjects:
Genomic imprinting
placenta
differentially methylated regions
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2025.2523191
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