Expression of TNF-α and Related Signaling Molecules in the Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients

Expression of TNF-α and Related Signaling Molecules in the Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients

We examined the role of tumor necrosis factor (TNF-α) and its related signaling intermediates leading to apoptosis/proliferation in the peripheral blood mononuclear cells (PBMCs) of RA patients. The constitutive expression of mRNA for TNF-α receptors (TNFR-I and TNFR-II) and the adapter molecules, s...

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Bibliographic Details
Main Authors: Sunil Kumar Raghav, Bhawna Gupta, Charu Agrawal, Ved P. Chaturvedi, Hasi R. Das
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/MI/2006/12682
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