A prospective study of risk factors of mortality in patients with eclampsia: a single center study
Objectives: To determine the risk factors affecting the mortality rate in women with eclampsia. Methods: This prospective observational cohort included 200 patients who presented with seizures or coma (eclampsia) which could not be attributed to other causes and admitted in the emergency (labour r...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Barpeta Obstetrics and Gynaecological Society
2024-12-01
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| Series: | New Indian Journal of OBGYN |
| Subjects: | |
| Online Access: | https://journal.barpetaogs.co.in/pdf/11155.pdf |
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| Summary: | Objectives: To determine the risk factors affecting the mortality rate in women with eclampsia. Methods: This
prospective observational cohort included 200 patients who presented with seizures or coma (eclampsia) which could
not be attributed to other causes and admitted in the emergency (labour room). The clinical, obstetric examination,
and examination pertinent to the signs and symptoms of hypertension and low haemoglobin were done. Laboratory
investigations were performed. The fetomaternal outcomes were determined in terms of mortality, mode of delivery,
and birth weight. Association of risk of mortality was evaluated in terms of demographic characteristics, obstetric
history, delivery details, and signs, symptoms and investigations. P-value <0.05 was considered statistically
significant. Results: Maternal death occurred in 37 (18.50%) patients. In 29.73% of patients, cause of maternal death
was acute pulmonary edema followed by DIC (13.51%). Socioeconomically, low class status, illiteracy, and rural
residence carried significantly higher odds of mortality with odds ratio of 1.27, 14.729, and 3.218, respectively.
Compared to survivors, those who died had significantly more undelivered pregnancies (40.54% vs. 0%, P<.0001);
significantly more instrumental delivery (13.64% vs. 2.45%), and significantly more preterms (54.55% vs. 33.13%).
Conclusion: In developing countries, eclampsia holds a significant association with maternal deaths, institutional
deliveries, and preterm birth. Appropriate caution and management should be done for eclamptic patients to decrease
the mortality and improve the fetomaternal outcomes. |
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| ISSN: | 2454-2334 2454-2342 |