Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan

Introduction. In Japan, the cost-effectiveness of total colonoscopy (TCS) for primary screening of colorectal cancer (CRC) is unclear. We compared the cost of identifying a patient with CRC using two primary screening strategies: TCS (strategy 1) and the immunochemical fecal test (FIT) (strategy 2)....

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Main Authors: Masau Sekiguchi, Takahisa Matsuda, Naoto Tamai, Taku Sakamoto, Takeshi Nakajima, Yosuke Otake, Yasuo Kakugawa, Yoshitaka Murakami, Yutaka Saito
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/728454
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author Masau Sekiguchi
Takahisa Matsuda
Naoto Tamai
Taku Sakamoto
Takeshi Nakajima
Yosuke Otake
Yasuo Kakugawa
Yoshitaka Murakami
Yutaka Saito
author_facet Masau Sekiguchi
Takahisa Matsuda
Naoto Tamai
Taku Sakamoto
Takeshi Nakajima
Yosuke Otake
Yasuo Kakugawa
Yoshitaka Murakami
Yutaka Saito
author_sort Masau Sekiguchi
collection DOAJ
description Introduction. In Japan, the cost-effectiveness of total colonoscopy (TCS) for primary screening of colorectal cancer (CRC) is unclear. We compared the cost of identifying a patient with CRC using two primary screening strategies: TCS (strategy 1) and the immunochemical fecal test (FIT) (strategy 2). Materials and Methods. We retrospectively analyzed the TCS screening database at our institution from February 2004 to August 2010 (strategy 1, 𝑛=15,348) and the Japanese nationwide survey of CRC screening in 2008 (strategy 2, 𝑛=5,267,443). Results. 112 and 6,838 CRC cases were detected in strategies 1 and 2, costing 2,124,000 JPY and 1,629,000 JPY, respectively. The rate of earlier-stage CRC was higher in strategy 1. Conclusions. The cost was higher using TCS as a primary screening procedure. However, the difference was not excessive, and considering the increased rate of detecting earlier CRC, the use of TCS as a primary screening tool may be cost-effective.
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institution Kabale University
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publishDate 2012-01-01
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spelling doaj-art-39cd62eb76d946ec883b64ed2ff1a3062025-08-20T03:55:11ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/728454728454Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in JapanMasau Sekiguchi0Takahisa Matsuda1Naoto Tamai2Taku Sakamoto3Takeshi Nakajima4Yosuke Otake5Yasuo Kakugawa6Yoshitaka Murakami7Yutaka Saito8Endoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanDepartment of Medical Statistics, Shiga University of Medical Science, Shiga 520-2192, JapanEndoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, JapanIntroduction. In Japan, the cost-effectiveness of total colonoscopy (TCS) for primary screening of colorectal cancer (CRC) is unclear. We compared the cost of identifying a patient with CRC using two primary screening strategies: TCS (strategy 1) and the immunochemical fecal test (FIT) (strategy 2). Materials and Methods. We retrospectively analyzed the TCS screening database at our institution from February 2004 to August 2010 (strategy 1, 𝑛=15,348) and the Japanese nationwide survey of CRC screening in 2008 (strategy 2, 𝑛=5,267,443). Results. 112 and 6,838 CRC cases were detected in strategies 1 and 2, costing 2,124,000 JPY and 1,629,000 JPY, respectively. The rate of earlier-stage CRC was higher in strategy 1. Conclusions. The cost was higher using TCS as a primary screening procedure. However, the difference was not excessive, and considering the increased rate of detecting earlier CRC, the use of TCS as a primary screening tool may be cost-effective.http://dx.doi.org/10.1155/2012/728454
spellingShingle Masau Sekiguchi
Takahisa Matsuda
Naoto Tamai
Taku Sakamoto
Takeshi Nakajima
Yosuke Otake
Yasuo Kakugawa
Yoshitaka Murakami
Yutaka Saito
Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
Gastroenterology Research and Practice
title Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
title_full Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
title_fullStr Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
title_full_unstemmed Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
title_short Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan
title_sort cost effectiveness of total colonoscopy in screening of colorectal cancer in japan
url http://dx.doi.org/10.1155/2012/728454
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