Vitamin K supports TGF-β1 depended in vitro human Langerhans cell differentiation and function via Axl

Vitamin K supports TGF-β1 depended in vitro human Langerhans cell differentiation and function via Axl

IntroductionOn the outermost edge of the body a dense network of dendritic cells (DCs), the so-called Langerhans cells (LCs), represents the first immune barrier. The establishment and maintenance of this epidermal network is dependent on the cytokine transforming growth factor-β1 (TGF-β1) expressed...

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Bibliographic Details
Main Authors: Thomas Bauer, Susanne Richter-Eder, Nighat Yasmin, Jennifer Jurkin, René Köffel, Herbert Strobl
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
dendritic cell
Langerhans cell
keratinocyte
transforming growth factor
receptor tyrosine kinase Axl
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1509228/full
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