Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report
Global pandemic of Coronavirus disease 2019 (COVID-19) have been developed with a respiratory infection as main symptom and vaccines had been proven against SARS-CoV-2 infection. We would like to present acute transverse myelitis with hypercoagulable condition case, after receiving the inactive SARS...
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| Language: | Indonesian |
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Indonesian Society of Neuroanesthesia & Critical Care (INA-SNACC)
2025-02-01
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| Series: | Jurnal Neuroanestesi Indonesia |
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| Online Access: | https://inasnacc.org/ojs2/index.php/jni/article/view/631 |
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| author | Lisda Amalia |
| author_facet | Lisda Amalia |
| author_sort | Lisda Amalia |
| collection | DOAJ |
| description | Global pandemic of Coronavirus disease 2019 (COVID-19) have been developed with a respiratory infection as main symptom and vaccines had been proven against SARS-CoV-2 infection. We would like to present acute transverse myelitis with hypercoagulable condition case, after receiving the inactive SARS-CoV-2 vaccine (SinoVac). Case Presentation: This is a case from a 20-year-old male with acute onset of flaccid paraplegia, hyporeflexia, loss of sensation below 5th thoracic level, loss of autonomic function, and a positive Babinski sign bilaterally on 7 days after receiving SARS-CoV-2 vaccine. From lumbar puncture examination, we found elevated liquor cerebrospinal protein with mononuclear cell predominantly and elevated d-dimer and also decreased fibrinogen levels from laboratory examination. From Magnetic Resonance Imaging (MRI) showed hyperintensity at the 5th until 9th thoracal level. He improved motoric strength of the lower limb (walking without assistance), numbness and pain, urine and fecal retention after receiving methylprednisolone for 3 days. Conclusion: Acute transverse myelitis with hypercoagulable state was a rare case associated with COVID-19 vaccination, but clinician should be aware for early detection and giving proper treatment. |
| format | Article |
| id | doaj-art-39b9c37a834c48d0bb01aa8757451f80 |
| institution | Kabale University |
| issn | 2088-9674 2460-2302 |
| language | Indonesian |
| publishDate | 2025-02-01 |
| publisher | Indonesian Society of Neuroanesthesia & Critical Care (INA-SNACC) |
| record_format | Article |
| series | Jurnal Neuroanestesi Indonesia |
| spelling | doaj-art-39b9c37a834c48d0bb01aa8757451f802025-08-20T03:48:42ZindIndonesian Society of Neuroanesthesia & Critical Care (INA-SNACC)Jurnal Neuroanestesi Indonesia2088-96742460-23022025-02-011412124https://doi.org/10.24244/jni.v14i1.631Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case ReportLisda Amalia0Department of Neurology, Medical Faculty, Universitas Padjadjaran/Hasan Sadikin General Hospital Bandung, IndonesiaGlobal pandemic of Coronavirus disease 2019 (COVID-19) have been developed with a respiratory infection as main symptom and vaccines had been proven against SARS-CoV-2 infection. We would like to present acute transverse myelitis with hypercoagulable condition case, after receiving the inactive SARS-CoV-2 vaccine (SinoVac). Case Presentation: This is a case from a 20-year-old male with acute onset of flaccid paraplegia, hyporeflexia, loss of sensation below 5th thoracic level, loss of autonomic function, and a positive Babinski sign bilaterally on 7 days after receiving SARS-CoV-2 vaccine. From lumbar puncture examination, we found elevated liquor cerebrospinal protein with mononuclear cell predominantly and elevated d-dimer and also decreased fibrinogen levels from laboratory examination. From Magnetic Resonance Imaging (MRI) showed hyperintensity at the 5th until 9th thoracal level. He improved motoric strength of the lower limb (walking without assistance), numbness and pain, urine and fecal retention after receiving methylprednisolone for 3 days. Conclusion: Acute transverse myelitis with hypercoagulable state was a rare case associated with COVID-19 vaccination, but clinician should be aware for early detection and giving proper treatment.https://inasnacc.org/ojs2/index.php/jni/article/view/631acute transverse myelitishypercoagulable state |
| spellingShingle | Lisda Amalia Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report Jurnal Neuroanestesi Indonesia acute transverse myelitis hypercoagulable state |
| title | Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report |
| title_full | Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report |
| title_fullStr | Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report |
| title_full_unstemmed | Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report |
| title_short | Inactivated SARS–CoV–2 Vaccine Inducing Acute Transverse Myelitis and Hypercoagulable State: A Case Report |
| title_sort | inactivated sars cov 2 vaccine inducing acute transverse myelitis and hypercoagulable state a case report |
| topic | acute transverse myelitis hypercoagulable state |
| url | https://inasnacc.org/ojs2/index.php/jni/article/view/631 |
| work_keys_str_mv | AT lisdaamalia inactivatedsarscov2vaccineinducingacutetransversemyelitisandhypercoagulablestateacasereport |