Genetic Polymorphism of <i>CYP2R1</i>, <i>CYP27A1</i>, <i>CYP27B1</i>, and Vitamin D Metabolites Plasma Levels in Patients with Cardiovascular Disease: A Pilot Study

Genetic Polymorphism of <i>CYP2R1</i>, <i>CYP27A1</i>, <i>CYP27B1</i>, and Vitamin D Metabolites Plasma Levels in Patients with Cardiovascular Disease: A Pilot Study

The active form of vitamin D, calcitriol (1,25(OH)<sub>2</sub>D<sub>3</sub>), is produced from 25(OH)D<sub>3</sub> via enzymes encoded by <i>CYP2R1</i>, <i>CYP27A1</i>, and <i>CYP27B1</i>. Polymorphisms in these genes may alter...

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Bibliographic Details
Main Authors: Mohamed Abouzid, Łukasz Kruszyna, Dominika Kaczmarek, Leonid Kagan, Aniceta Ada Mikulska-Sauermann, Dorota Filipowicz, Matylda Resztak, Franciszek K. Główka, Marta Karaźniewicz-Łada
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomolecules
Subjects:
<i>CYP2R1</i>
<i>CYP27A1</i>
<i>CYP27B1</i>
calcitriol
calcidiol
cardiovascular disease
Online Access:https://www.mdpi.com/2218-273X/15/5/699
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