LOCAL THERAPY BY KENALOG OF PATIENTS WITH RHEUMATOID ARTHRITIS
Objective. To asses the dependence of the efficacy of Kenalog intraarticular injections on the disease activity according the index of the number of joints needing treatment. Material ami methods. 50 RA pts with insufficient effect of systemic drug treatment of inflamma- tory changes in joints (45 f...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA PRESS LLC
2001-10-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/606 |
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| Summary: | Objective. To asses the dependence of the efficacy of Kenalog intraarticular injections on the disease activity according the index of the number of joints needing treatment. Material ami methods. 50 RA pts with insufficient effect of systemic drug treatment of inflamma- tory changes in joints (45 females and 5 males) aged 18-77 (median age 53.0±13.0). Disease duration varied from 6 months to 30 years (median 11.5±7.9 years). Results. 50 pts had 495 Kenalog intraarticular injections. 31 pts had no more than 3 joints (median 1. 9±0.8), 19 pts had injections into 4 and more joints (median 5.9±1.5). Duration of improvement after single Kenalog injection in both did not differ significantly (3.4±3.2 months in the 1st group and 4.3±6.2 months in the 2nd). Conclusion, active inflammation persisted in a few of joints inspite of the effective in the whole systemic therapy, periodic intraarticular Kenalog injections can time be used for a long as an active assisting treatment completing the basic therapy. In cases of persisting polyarthritis not responding to systemic therapy Kenalog administration into inflamed joints can not only complement but also substitute the systemic steroid therapy for some time |
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| ISSN: | 1995-4484 1995-4492 |