Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation
Abstract Background Infective aortitis (IA) with vegetation formation is a rare but potentially life-threatening complication in patients with heart transplantation (HTx). IA caused by Corynebacterium striatum (C. striatum) has scarcely been reported. Herein, we present a case of IA caused by C. str...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-025-11431-2 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849226562687205376 |
|---|---|
| author | Wei Xiang Ling-Yun Kong Peng Zou Dong-Yan Shen Xiu-Juan Wang Fang Liu |
| author_facet | Wei Xiang Ling-Yun Kong Peng Zou Dong-Yan Shen Xiu-Juan Wang Fang Liu |
| author_sort | Wei Xiang |
| collection | DOAJ |
| description | Abstract Background Infective aortitis (IA) with vegetation formation is a rare but potentially life-threatening complication in patients with heart transplantation (HTx). IA caused by Corynebacterium striatum (C. striatum) has scarcely been reported. Herein, we present a case of IA caused by C. striatum in a young man eight months after his second orthotopic HTx. Case presentation We present a case of IA caused by C. striatum in a young man eight months after his second orthotopic HTx. The clinical course was complicated by recurrent fever, persistent bacteremia, anemia, and multiple peripheral arterial embolisms. While transthoracic echocardiography (TTE) revealed normal cardiac valves and endocardium, transesophageal echocardiography (TEE) confirmed an intraluminal mass in the anastomotic site of ascending aortic. The patient declined surgical intervention but responded well to medical therapy. He got resolution of infection following 6 weeks of vancomycin and remained well upon 34 months of follow-up without recurrent fever or new embolic events. Conclusions This case highlights the importance of evaluating the anastomotic site of ascending aortic in the context of bacteremia for HTx recipients, especially when routine TTE shows no valvular or endocardial involvement. |
| format | Article |
| id | doaj-art-39991c207f99495ab3b1e3776536f2bf |
| institution | Kabale University |
| issn | 1471-2334 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj-art-39991c207f99495ab3b1e3776536f2bf2025-08-24T11:10:09ZengBMCBMC Infectious Diseases1471-23342025-08-012511410.1186/s12879-025-11431-2Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantationWei Xiang0Ling-Yun Kong1Peng Zou2Dong-Yan Shen3Xiu-Juan Wang4Fang Liu5Cardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua UniversityCardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua UniversityCardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua UniversityCardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua UniversityCardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua UniversityCardiovascular center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua UniversityAbstract Background Infective aortitis (IA) with vegetation formation is a rare but potentially life-threatening complication in patients with heart transplantation (HTx). IA caused by Corynebacterium striatum (C. striatum) has scarcely been reported. Herein, we present a case of IA caused by C. striatum in a young man eight months after his second orthotopic HTx. Case presentation We present a case of IA caused by C. striatum in a young man eight months after his second orthotopic HTx. The clinical course was complicated by recurrent fever, persistent bacteremia, anemia, and multiple peripheral arterial embolisms. While transthoracic echocardiography (TTE) revealed normal cardiac valves and endocardium, transesophageal echocardiography (TEE) confirmed an intraluminal mass in the anastomotic site of ascending aortic. The patient declined surgical intervention but responded well to medical therapy. He got resolution of infection following 6 weeks of vancomycin and remained well upon 34 months of follow-up without recurrent fever or new embolic events. Conclusions This case highlights the importance of evaluating the anastomotic site of ascending aortic in the context of bacteremia for HTx recipients, especially when routine TTE shows no valvular or endocardial involvement.https://doi.org/10.1186/s12879-025-11431-2Infective aortitisHeart transplantationCorynebacterium striatumVegetation |
| spellingShingle | Wei Xiang Ling-Yun Kong Peng Zou Dong-Yan Shen Xiu-Juan Wang Fang Liu Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation BMC Infectious Diseases Infective aortitis Heart transplantation Corynebacterium striatum Vegetation |
| title | Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation |
| title_full | Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation |
| title_fullStr | Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation |
| title_full_unstemmed | Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation |
| title_short | Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation |
| title_sort | infective aortitis caused by corynebacterium striatum in a patient with twice orthotopic heart transplantation |
| topic | Infective aortitis Heart transplantation Corynebacterium striatum Vegetation |
| url | https://doi.org/10.1186/s12879-025-11431-2 |
| work_keys_str_mv | AT weixiang infectiveaortitiscausedbycorynebacteriumstriatuminapatientwithtwiceorthotopichearttransplantation AT lingyunkong infectiveaortitiscausedbycorynebacteriumstriatuminapatientwithtwiceorthotopichearttransplantation AT pengzou infectiveaortitiscausedbycorynebacteriumstriatuminapatientwithtwiceorthotopichearttransplantation AT dongyanshen infectiveaortitiscausedbycorynebacteriumstriatuminapatientwithtwiceorthotopichearttransplantation AT xiujuanwang infectiveaortitiscausedbycorynebacteriumstriatuminapatientwithtwiceorthotopichearttransplantation AT fangliu infectiveaortitiscausedbycorynebacteriumstriatuminapatientwithtwiceorthotopichearttransplantation |