Terminal ileitis: Questions of differential diagnosis and prospects for treatment. A review

Idiopathic terminal ileitis (ITI) occurs in 0.5–7% of people. It is believed that in some of them the cause of ITI can be established over time, in some of them Crohn's disease develops, in a greater number of patients ITI is asymptomatic and capable of self-resolution. Diagnosis of the causes...

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Bibliographic Details
Main Authors: Alexey M. Osadchuk, Oleg V. Golovenko, Irina D. Loranskaia
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2025-01-01
Series:Терапевтический архив
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Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/646536/194500
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Summary:Idiopathic terminal ileitis (ITI) occurs in 0.5–7% of people. It is believed that in some of them the cause of ITI can be established over time, in some of them Crohn's disease develops, in a greater number of patients ITI is asymptomatic and capable of self-resolution. Diagnosis of the causes of terminal ileitis is difficult, and the choice of therapeutic tactics is complex. This is largely due to the lack of clinical guidelines for the treatment of ITI. The article is devoted to the development of an algorithm for the diagnosis and treatment of ITI, which determines its relevance. It is shown that in the case of asymptomatic ITI, drug therapy is not required, in the presence of symptomatic ITI involving only the mucous membrane, therapy should be started with the prescription of mesalazine, and if transmural damage to the wall of the terminal ileum is detected – with budesonide.
ISSN:0040-3660
2309-5342