Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination
The most common adverse effects of SARS-CoV-2 vaccines are injection site reactions and systemic symptoms, such as fever and malaise, which are typically self-limiting. Multisystem inflammatory syndrome after SARS-CoV-2 vaccination (MIS-V) is rare. In this report, we describe a case of a 22-year-old...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2022-11-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0747 |
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| author | Yuki Shimada Masao Takigami Shunya Kaneshita Kenji Yanishi Satoaki Matoba Yutaka Kawahito |
| author_facet | Yuki Shimada Masao Takigami Shunya Kaneshita Kenji Yanishi Satoaki Matoba Yutaka Kawahito |
| author_sort | Yuki Shimada |
| collection | DOAJ |
| description | The most common adverse effects of SARS-CoV-2 vaccines are injection site reactions and systemic symptoms, such as fever and malaise, which are typically self-limiting. Multisystem inflammatory syndrome after SARS-CoV-2 vaccination (MIS-V) is rare. In this report, we describe a case of a 22-year-old man who developed MIS-V with myocardial infarction. Optical coherence tomography (OCT) showed blurring of intravascular structure, intimal thickening, and medial vessel destruction. High-dose glucocorticoid and antithrombotic therapy were effective as shown through improvement in OCT findings. |
| format | Article |
| id | doaj-art-397aa1bd1ac94512a872c19fca5dfe8d |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-397aa1bd1ac94512a872c19fca5dfe8d2025-08-20T03:18:45ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-11-011910.7326/aimcc.2022.0747Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 VaccinationYuki Shimada0Masao Takigami1Shunya Kaneshita2Kenji Yanishi3Satoaki Matoba4Yutaka Kawahito51Department of Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan2Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan1Department of Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan2Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan2Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan1Department of Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, JapanThe most common adverse effects of SARS-CoV-2 vaccines are injection site reactions and systemic symptoms, such as fever and malaise, which are typically self-limiting. Multisystem inflammatory syndrome after SARS-CoV-2 vaccination (MIS-V) is rare. In this report, we describe a case of a 22-year-old man who developed MIS-V with myocardial infarction. Optical coherence tomography (OCT) showed blurring of intravascular structure, intimal thickening, and medial vessel destruction. High-dose glucocorticoid and antithrombotic therapy were effective as shown through improvement in OCT findings.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0747 |
| spellingShingle | Yuki Shimada Masao Takigami Shunya Kaneshita Kenji Yanishi Satoaki Matoba Yutaka Kawahito Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination Annals of Internal Medicine: Clinical Cases |
| title | Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination |
| title_full | Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination |
| title_fullStr | Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination |
| title_full_unstemmed | Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination |
| title_short | Multisystem Inflammatory Syndrome Leading to Myocardial Infarction After SARS-CoV-2 Vaccination |
| title_sort | multisystem inflammatory syndrome leading to myocardial infarction after sars cov 2 vaccination |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2022.0747 |
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