Macrophage regulated cell death: implications and mechanisms in organ transplantation

Macrophage regulated cell death: implications and mechanisms in organ transplantation

Organ transplantation is a critical treatment for end-stage organ failure, but long-term graft survival remains suboptimal due to ischemia-reperfusion injury (IRI) and transplant rejection. The immune microenvironment, especially macrophages, plays a key role in these processes. Various forms of reg...

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Bibliographic Details
Main Authors: Jincheng Hou, Chenghao Li, Geng Li, Wai Yen Yim, Bingchuan Geng, Yuqi Cheng, Zihao Wang, Zhengfeng Fan, Fuqiang Tong, Jiawei Shi, Yixuan Wang, Nianguo Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
macrophage cell
regulated cell death (RCD)
organ transplantation
ischemia-reperfusion injury
transplant rejection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1604429/full
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