Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in progeny

Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in progeny

A number of dysfunctions of congenital and adaptive components of the immune system are observed in progeny of rats with experimental gestational diabetes (EGD). The key link in pathogenesis of EGD and other diseases is the activation of NLRP3-inflammasome. Therefore, it is an attractive target for...

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Bibliographic Details
Main Authors: Т. М. Prozorova, V. A. Kamyshna, О. М. Kamyshnyi
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2017-08-01
Series:Patologìâ
Subjects:
EGD
MLN
NLRP3-inflammasome
glibenclamide
Online Access:http://pat.zsmu.edu.ua/article/view/109269/105909
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