The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway.

The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway.

FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in xenograft models, when administered exogenously. However, the role of endogenous FKBPL in angiogenesis is not well characterised. Here we investigate...

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Bibliographic Details
Main Authors: Anita Yakkundi, Lynn McCallum, Anthony O'Kane, Hayder Dyer, Jenny Worthington, Hayley D McKeen, Lana McClements, Christopher Elliott, Helen O McCarthy, David G Hirst, Tracy Robson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0055075&type=printable
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