Ulcerative colitis: STRIDE-ing beyond symptoms with new standards
The landscape of ulcerative colitis has changed in the last two decades. Advancements in pharmacotherapeutics have heralded the introduction of new treatment options, with many agents in development. Better clinical outcomes are seen with tighter disease control, made possible with greater understan...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer – Medknow Publications
2024-02-01
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| Series: | Singapore Medical Journal |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.11622/smedj.2021173 |
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| _version_ | 1823863752170143744 |
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| author | Shu Wen Tay Kevin Kim Jun Teh Tiing-Leong Ang Malcolm Tan |
| author_facet | Shu Wen Tay Kevin Kim Jun Teh Tiing-Leong Ang Malcolm Tan |
| author_sort | Shu Wen Tay |
| collection | DOAJ |
| description | The landscape of ulcerative colitis has changed in the last two decades. Advancements in pharmacotherapeutics have heralded the introduction of new treatment options, with many agents in development. Better clinical outcomes are seen with tighter disease control, made possible with greater understanding of inflammatory pathways and their blockade with drugs. There has been a resultant shift in treatment targets, beyond symptoms to endoscopic and histological healing. Controlling the burden of disease activity also lowers the risk of developing colorectal cancer. Colorectal cancer screening now requires the use of dye-based agents and high-definition colonoscopy to improve the detection of colonic neoplasms. |
| format | Article |
| id | doaj-art-39613577f7424733b8acd016e2b1c8b1 |
| institution | Kabale University |
| issn | 0037-5675 2737-5935 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Wolters Kluwer – Medknow Publications |
| record_format | Article |
| series | Singapore Medical Journal |
| spelling | doaj-art-39613577f7424733b8acd016e2b1c8b12025-02-09T10:19:31ZengWolters Kluwer – Medknow PublicationsSingapore Medical Journal0037-56752737-59352024-02-016529910510.11622/smedj.2021173Ulcerative colitis: STRIDE-ing beyond symptoms with new standardsShu Wen TayKevin Kim Jun TehTiing-Leong AngMalcolm TanThe landscape of ulcerative colitis has changed in the last two decades. Advancements in pharmacotherapeutics have heralded the introduction of new treatment options, with many agents in development. Better clinical outcomes are seen with tighter disease control, made possible with greater understanding of inflammatory pathways and their blockade with drugs. There has been a resultant shift in treatment targets, beyond symptoms to endoscopic and histological healing. Controlling the burden of disease activity also lowers the risk of developing colorectal cancer. Colorectal cancer screening now requires the use of dye-based agents and high-definition colonoscopy to improve the detection of colonic neoplasms.https://journals.lww.com/10.11622/smedj.2021173biologic therapybiosimilarsinflammatory bowel diseasetreat to targetulcerative colitis |
| spellingShingle | Shu Wen Tay Kevin Kim Jun Teh Tiing-Leong Ang Malcolm Tan Ulcerative colitis: STRIDE-ing beyond symptoms with new standards Singapore Medical Journal biologic therapy biosimilars inflammatory bowel disease treat to target ulcerative colitis |
| title | Ulcerative colitis: STRIDE-ing beyond symptoms with new standards |
| title_full | Ulcerative colitis: STRIDE-ing beyond symptoms with new standards |
| title_fullStr | Ulcerative colitis: STRIDE-ing beyond symptoms with new standards |
| title_full_unstemmed | Ulcerative colitis: STRIDE-ing beyond symptoms with new standards |
| title_short | Ulcerative colitis: STRIDE-ing beyond symptoms with new standards |
| title_sort | ulcerative colitis stride ing beyond symptoms with new standards |
| topic | biologic therapy biosimilars inflammatory bowel disease treat to target ulcerative colitis |
| url | https://journals.lww.com/10.11622/smedj.2021173 |
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